Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | GABRP | O00591 | 1/20 | 0.50 |
| ▸ | GABRD | O14764 | 1/20 | 0.50 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.50 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.50 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.50 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.50 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.50 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.50 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.50 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.50 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.50 |
| ▸ | GABRE | P78334 | 1/20 | 0.50 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.50 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.50 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.50 |
| ▸ | GABRQ | Q9UN88 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29114946 | 0.86 | SMN1; SMN2 (0.54) | LMNAALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL29115107 | 0.85 | KMT2A (0.56) | MAPTLMNAALDH1A1MAPK1MEN1 | |
| SCHEMBL29114956 | 0.84 | PTPN1 (0.53) | MAPTLMNAALDH1A1MEN1KMT2A | |
| SCHEMBL29114965 | 0.82 | DYRK1A (0.51) | MAPTMEN1KMT2ASMN1; SMN2DYRK1A | |
| SCHEMBL30683706 | 0.80 | LMNA (0.53) | MAPTLMNAALDH1A1MEN1KMT2A | |
| SCHEMBL29114917 | 0.80 | LMNA (0.53) | MAPTLMNAALDH1A1MEN1KMT2A | |
| SCHEMBL29114968 | 0.79 | SMN1; SMN2 (0.61) | MAPTLMNAALDH1A1MAPK1MEN1 | |
| SCHEMBL29114941 | 0.78 | POLB (0.50) | MAPTLMNAALDH1A1MEN1KMT2A | |
| SCHEMBL1413988 | 0.77 | DYRK1A (0.61) | MAPTLMNAALDH1A1MAPK1MEN1 | |
| SCHEMBL9976032 | 0.75 | MAPT (0.62) | MAPTALDH1A1MAPK1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117143019-A | As beta 2 Pyrazole amide derivatives of allosteric antagonists of the adrenergic receptors | 常州大学 | 2023-12-01 | — | — | CN | disclosed |