Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 9/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | TACR1 | P25103 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.34 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | SYK | P43405 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4730702 | 0.92 | MAPT (0.41) | MAPTCHRM3ALDH1A1TACR1MEN1 | |
| SCHEMBL4733534 | 0.85 | AKR1C3 (0.35) | MAPTCHRM3ALDH1A1MEN1LMNA | |
| SCHEMBL4734232 | 0.84 | MAPT (0.41) | MAPTCHRM3ALDH1A1TACR1MEN1 | |
| SCHEMBL4730073 | 0.84 | CA2 (0.39) | ALDH1A1MEN1KMT2APTGS2 | |
| SCHEMBL4730301 | 0.84 | MAPT (0.40) | MAPTALDH1A1MEN1KMT2AL3MBTL1 | |
| SCHEMBL2911519 | 0.83 | CHRM3 (0.43) | MAPTCHRM3ALDH1A1TACR1 | |
| SCHEMBL2905171 | 0.80 | CHRM3 (0.42) | MAPTCHRM3MEN1LMNAKMT2A | |
| SCHEMBL4729048 | 0.79 | RXFP1 (0.35) | CHRM3ALDH1A1TACR1MEN1LMNA | |
| SCHEMBL4732975 | 0.79 | CA12 (0.44) | MAPTMEN1KMT2APTGS2 | |
| SCHEMBL4599063 | 0.73 | TSHR (0.43) | MAPTALDH1A1MEN1LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008053044-A2 | HETARYL CARBON ACID-N-(BIPHEN-2-YL)AMIDE COMPOUNDS | BASF SE (DE) | 2008-05-08 | — | — | WO | claimed |