Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KCNK2 | O95069 | 2/20 | 0.36 |
| ▸ | KCNK10 | P57789 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.35 |
| ▸ | TACR1 | P25103 | 1/20 | 0.35 |
| ▸ | KIF11 | P52732 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4730702 | 0.91 | MAPT (0.41) | MAPTALDH1A1KCNK2CHRM3TACR1 | |
| SCHEMBL4733183 | 0.87 | SMN1; SMN2 (0.36) | MAPTKCNK2KCNK10CHRM3TACR1 | |
| SCHEMBL4733535 | 0.84 | MAPT (0.41) | MAPTALDH1A1CHRM3TACR1MEN1 | |
| SCHEMBL4732975 | 0.83 | CA12 (0.44) | MAPTSMN1; SMN2MEN1KMT2APOLB | |
| SCHEMBL2911519 | 0.83 | CHRM3 (0.43) | MAPTALDH1A1CHRM3TACR1NPC1 | |
| SCHEMBL4730301 | 0.82 | MAPT (0.40) | MAPTALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL2905171 | 0.80 | CHRM3 (0.42) | MAPTCHRM3SMN1; SMN2MEN1LMNA | |
| SCHEMBL3034001 | 0.80 | CHRM3 (0.39) | MAPTALDH1A1KCNK2KCNK10CHRM3 | |
| SCHEMBL4730073 | 0.79 | CA2 (0.39) | ALDH1A1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL4729048 | 0.78 | RXFP1 (0.35) | ALDH1A1KCNK2CHRM3TACR1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008053044-A2 | HETARYL CARBON ACID-N-(BIPHEN-2-YL)AMIDE COMPOUNDS | BASF SE (DE) | 2008-05-08 | — | — | WO | claimed |
| WO-2008053044-A2 | HETARYL CARBON ACID-N-(BIPHEN-2-YL)AMIDE COMPOUNDS | BASF SE (DE) | 2008-05-08 | — | — | WO | disclosed |