SCHEMBL29115481

SCHEMBL29115481

Nc1ccc(C(=O)CF)c(F)c1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.41
KDM4E B2RXH2 3/20 0.41
ALDH1A1 P00352 3/20 0.41
CYP3A4 P08684 3/20 0.41
GAA P10253 2/20 0.41
PTPN1 P18031 2/20 0.41
ESR2 Q92731 1/20 0.41
CRBN Q96SW2 1/20 0.40
CES2 O00748 1/20 0.39
CES1 P23141 1/20 0.39
TDP1 Q9NUW8 3/20 0.39
POLB P06746 2/20 0.39
DGAT1 O75907 1/20 0.39
MEN1 O00255 2/20 0.37
THRB P10828 2/20 0.37
RECQL P46063 2/20 0.37
KMT2A Q03164 2/20 0.37
KDR P35968 2/20 0.37
USP2 O75604 1/20 0.37
PKM P14618 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28524236 0.85 MAPT (0.41) MAPTKDM4EALDH1A1CYP3A4GAA
SCHEMBL14047784 0.83 HSP90AB1 (0.46) MAPTKDM4EALDH1A1CYP3A4GAA
SCHEMBL8584 0.80 CES2 (0.63) CES2CES1ACKR3
SCHEMBL101125 0.78 ALDH1A1 (0.61) MAPTKDM4EALDH1A1CYP3A4GAA
SCHEMBL30708577 0.78 ALDH1A1 (0.61) MAPTKDM4EALDH1A1CYP3A4GAA
SCHEMBL113659 0.78 DGAT1 (0.62) MAPTKDM4EALDH1A1CYP3A4GAA
SCHEMBL26972103 0.78 ALDH1A1 (0.61) MAPTKDM4EALDH1A1CYP3A4GAA
SCHEMBL23754470 0.77 DGAT1 (0.61) ALDH1A1GAACES2CES1DGAT1
SCHEMBL6632953 0.77 MEN1 (0.43) MAPTKDM4ECES2CES1POLB
SCHEMBL31612915 0.76 ALDH1A1 (0.52) MAPTKDM4EALDH1A1CYP3A4GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116854621-A Photosensitizer taking pentamethine cyanine dye as matrix, and synthesis method and application thereof 大连理工大学 2023-10-10 CN disclosed