SCHEMBL29115684

SCHEMBL29115684

O=[N+]([O-])c1cc(F)nc([N+](=O)[O-])c1

nearest known ligand 0.43

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 1/20 0.43
TSHR P16473 4/20 0.40
ALDH1A1 P00352 5/20 0.39
HIF1A Q16665 1/20 0.38
LMNA P02545 3/20 0.37
VCAM1 P19320 1/20 0.36
MEN1 O00255 1/20 0.36
HTT P42858 1/20 0.36
KMT2A Q03164 1/20 0.36
TXNRD1 Q16881 1/20 0.36
TXNRD3 Q86VQ6 1/20 0.36
TXNRD2 Q9NNW7 1/20 0.36
CYP3A4 P08684 2/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
TDP1 Q9NUW8 3/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3293139 0.84 CYP19A1 (0.52) CYP19A1TSHRALDH1A1LMNAVCAM1
SCHEMBL7690047 0.75 ALDH1A1 (0.45) CYP19A1TSHRALDH1A1HTTCYP3A4
SCHEMBL4494414 0.68 LMNA (0.38) TSHRALDH1A1LMNAMEN1KMT2A
SCHEMBL212845 0.68 CYP19A1 (0.81) CYP19A1TSHRALDH1A1HIF1ALMNA
SCHEMBL1172437 0.67 CYP19A1 (0.55) CYP19A1TSHRALDH1A1HIF1ALMNA
SCHEMBL7203812 0.67 CYP19A1 (0.62) CYP19A1TSHRALDH1A1HIF1ALMNA
SCHEMBL23829919 0.67 ALDH1A1 (0.47) TSHRALDH1A1HIF1ALMNATXNRD1
SCHEMBL28234952 0.66 ALDH1A1 (0.51) TSHRALDH1A1HIF1AHTTTXNRD1
SCHEMBL31067258 0.66 ALDH1A1 (0.51) TSHRALDH1A1HIF1AHTTTXNRD1
SCHEMBL239666 0.66 CYP19A1 (0.52) CYP19A1TSHRALDH1A1HIF1ALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117069643-A Novel free radical monomer containing diphenylamine derivative structure, polymer, preparation method and application thereof 武汉理工大学 2023-11-17 CN disclosed