Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR2 | O95136 | 1/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.32 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.32 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 3/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.31 |
| ▸ | APAF1 | O14727 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 2/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | RAD52 | P43351 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20828899 | 0.81 | — | — | |
| SCHEMBL20819697 | 0.79 | L3MBTL1 (0.39) | S1PR2S1PR1S1PR3LPAR2CYP3A4 | |
| SCHEMBL29118537 | 0.78 | S1PR1 (0.33) | S1PR2S1PR1S1PR3LPAR2THRB | |
| SCHEMBL20828969 | 0.75 | ESR1 (0.33) | MAPTL3MBTL1NPSR1 | |
| SCHEMBL20828647 | 0.71 | — | — | |
| SCHEMBL6911178 | 0.71 | CNR1 (0.32) | S1PR2S1PR1S1PR3LPAR2PTGS2 | |
| SCHEMBL30617453 | 0.67 | RARB (0.37) | S1PR2S1PR1S1PR3LPAR2HTT | |
| SCHEMBL20819699 | 0.67 | RARB (0.37) | S1PR2S1PR1S1PR3LPAR2HTT | |
| SCHEMBL27959518 | 0.67 | PTGS2 (0.54) | PTGS2CYP3A4HTTMAPK1NPC1 | |
| SCHEMBL22011181 | 0.66 | PGAM1 (0.42) | L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111094513-B | Derivatives of dibenzofuran and dibenzothiophene | 默克专利股份有限公司 | 2023-11-03 | — | — | CN | disclosed |
| CN-111094513-A | Dibenzofurane and dibenzothiophene derivatives | 默克专利股份有限公司 | 2020-05-01 | — | — | CN | disclosed |