Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN5A | Q14524 | 11/20 | 0.65 |
| ▸ | KCNH2 | Q12809 | 12/20 | 0.61 |
| ▸ | CSF1R | P07333 | 7/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2913360 | 0.90 | SCN5A (0.52) | SCN5AKCNH2CSF1R | |
| SCHEMBL2909682 | 0.85 | CSF1R (0.64) | SCN5AKCNH2CSF1R | |
| SCHEMBL2911756 | 0.84 | KCNH2 (0.68) | SCN5AKCNH2CSF1R | |
| SCHEMBL2913426 | 0.82 | CSF1R (0.51) | SCN5AKCNH2CSF1R | |
| SCHEMBL2909211 | 0.80 | CSF1R (0.51) | SCN5AKCNH2CSF1R | |
| SCHEMBL2911892 | 0.79 | KCNH2 (0.76) | SCN5AKCNH2CSF1R | |
| SCHEMBL1276807 | 0.79 | SCN5A (1.00) | SCN5AKCNH2CSF1R | |
| SCHEMBL2907904 | 0.79 | KCNH2 (0.50) | SCN5AKCNH2CSF1R | |
| SCHEMBL2912641 | 0.78 | CSF1R (0.60) | SCN5AKCNH2CSF1R | |
| SCHEMBL2913869 | 0.78 | CSF1R (0.86) | SCN5AKCNH2CSF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2010496-B1 | 4-ANILINOQUINOLINE-3-CARBOXAMIDES AS CSF-1R KINASE INHIBITORS | ASTRAZENECA AB (SE) | 2010-08-25 | — | — | EP | disclosed |