Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 12/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | LTA4H | P09960 | 1/20 | 0.45 |
| ▸ | FPR2 | P25090 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | XBP1 | P17861 | 1/20 | 0.40 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.40 |
| ▸ | LIPE | Q05469 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29123534 | 0.91 | MAPK1 (0.44) | SCN9ALMNAMAPTFFAR1 | |
| SCHEMBL29123393 | 0.88 | SCN9A (0.54) | SCN9ALMNALTA4HFPR2FFAR1 | |
| SCHEMBL29123397 | 0.88 | SCN9A (0.54) | SCN9ALMNALTA4HFPR2FFAR1 | |
| SCHEMBL29123609 | 0.82 | SCN9A (0.47) | SCN9ALMNALTA4HFPR2MAPT | |
| SCHEMBL30006191 | 0.82 | SCN9A (0.47) | SCN9ALMNALTA4HFPR2MAPT | |
| SCHEMBL30689380 | 0.81 | LMNA (0.54) | SCN9ALMNALTA4HFPR2MAPT | |
| SCHEMBL30689299 | 0.81 | FFAR1 (0.51) | SCN9ALMNALTA4HFPR2MAPT | |
| SCHEMBL27171425 | 0.81 | SCN9A (0.50) | SCN9ALMNALTA4HFPR2MAPT | |
| SCHEMBL27204771 | 0.81 | SCN9A (0.50) | SCN9ALMNALTA4HFPR2MAPT | |
| SCHEMBL27204647 | 0.80 | LTA4H (0.67) | SCN9ALMNALTA4HFPR2FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117015537-A | Heteroaryl aminopropanol derivatives as inhibitors of LTA4H | 诺华股份有限公司 | 2023-11-07 | — | — | CN | disclosed |