Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 19/20 | 0.53 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24665389 | 0.91 | LTA4H (0.49) | LTA4HSCN9A | |
| SCHEMBL30005335 | 0.91 | LTA4H (0.49) | LTA4HSCN9A | |
| SCHEMBL30006042 | 0.91 | LTA4H (0.56) | LTA4H | |
| SCHEMBL29123681 | 0.91 | LTA4H (0.56) | LTA4H | |
| SCHEMBL24665399 | 0.91 | LTA4H (0.56) | LTA4H | |
| SCHEMBL27204693 | 0.86 | GRN (0.42) | SCN9A | |
| SCHEMBL27171436 | 0.86 | GRN (0.42) | SCN9A | |
| SCHEMBL29123472 | 0.86 | GRN (0.42) | SCN9A | |
| SCHEMBL29123537 | 0.84 | MAPK1 (0.42) | SCN9A | |
| SCHEMBL29123526 | 0.84 | PTPN1 (0.42) | SCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117015537-A | Heteroaryl aminopropanol derivatives as inhibitors of LTA4H | 诺华股份有限公司 | 2023-11-07 | — | — | CN | disclosed |