Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 3/20 | 0.42 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.41 |
| ▸ | GRN | P28799 | 2/20 | 0.40 |
| ▸ | SORT1 | Q99523 | 2/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | NPPA | P01160 | 1/20 | 0.37 |
| ▸ | MME | P08473 | 1/20 | 0.37 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.37 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.37 |
| ▸ | ACE | P12821 | 1/20 | 0.37 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.36 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29123464 | 0.92 | SCN9A (0.41) | PTPN1SCN9AGRNSORT1NPPA | |
| SCHEMBL24665374 | 0.91 | PTPN1 (0.39) | PTPN1SCN9AGRNSORT1FFAR1 | |
| SCHEMBL30005383 | 0.90 | LTA4H (0.38) | SCN9AGRNSORT1FFAR1MAPT | |
| SCHEMBL24665373 | 0.90 | LTA4H (0.38) | SCN9AGRNSORT1FFAR1MAPT | |
| SCHEMBL29123537 | 0.89 | MAPK1 (0.42) | PTPN1SCN9AGRNSORT1FFAR1 | |
| SCHEMBL27204693 | 0.88 | GRN (0.42) | PTPN1SCN9AGRNSORT1FFAR1 | |
| SCHEMBL29123472 | 0.88 | GRN (0.42) | PTPN1SCN9AGRNSORT1FFAR1 | |
| SCHEMBL27171436 | 0.88 | GRN (0.42) | PTPN1SCN9AGRNSORT1FFAR1 | |
| SCHEMBL24665315 | 0.84 | PPARD (0.42) | PTPN1SCN9AMAPTP2RX3 | |
| SCHEMBL29123439 | 0.84 | LTA4H (0.53) | SCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117015537-A | Heteroaryl aminopropanol derivatives as inhibitors of LTA4H | 诺华股份有限公司 | 2023-11-07 | — | — | CN | disclosed |