Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | SCN9A | Q15858 | 10/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29123607 | 0.91 | SCN9A (0.49) | SCN9AMAPTLMNAFFAR1 | |
| SCHEMBL29123469 | 0.88 | SCN9A (0.46) | MAPK1SCN9AFFAR1GAA | |
| SCHEMBL29123473 | 0.88 | SCN9A (0.46) | MAPK1SCN9AFFAR1GAA | |
| SCHEMBL29123679 | 0.85 | LTA4H (0.56) | — | |
| SCHEMBL24664167 | 0.83 | MAPK1 (0.42) | MAPK1SCN9AMAPTLMNARAB9A | |
| SCHEMBL29123536 | 0.83 | MAPK1 (0.42) | MAPK1SCN9AMAPTLMNARAB9A | |
| SCHEMBL29123324 | 0.81 | LTA4H (0.54) | MAPK1SCN9AMAPTFFAR1GAA | |
| SCHEMBL24664170 | 0.81 | LTA4H (0.54) | MAPK1SCN9AMAPTFFAR1GAA | |
| SCHEMBL29123537 | 0.81 | MAPK1 (0.42) | MAPK1SCN9AMAPTLMNARAB9A | |
| SCHEMBL30006916 | 0.80 | MAPK1 (0.51) | MAPK1SCN9AMAPTFFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117015537-A | Heteroaryl aminopropanol derivatives as inhibitors of LTA4H | 诺华股份有限公司 | 2023-11-07 | — | — | CN | disclosed |