Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.36 |
| ▸ | LTA4H | P09960 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | IDH1 | O75874 | 2/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.34 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.34 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30731757 | 1.00 | MAPT (0.38) | MAPTFFAR1LTA4HTHRBTP53 | |
| SCHEMBL29123425 | 0.91 | LTA4H (0.44) | MAPTLTA4HTP53SMN1; SMN2SCN9A | |
| SCHEMBL30731710 | 0.91 | LTA4H (0.44) | MAPTLTA4HTP53SMN1; SMN2SCN9A | |
| SCHEMBL30731741 | 0.88 | SCN9A (0.39) | MAPTFFAR1LTA4HTHRBTP53 | |
| SCHEMBL29123657 | 0.88 | SCN9A (0.39) | MAPTFFAR1LTA4HTHRBTP53 | |
| SCHEMBL29123730 | 0.85 | LTA4H (0.42) | MAPTFFAR1LTA4HTHRBTP53 | |
| SCHEMBL29123726 | 0.85 | LTA4H (0.42) | MAPTFFAR1LTA4HTHRBTP53 | |
| SCHEMBL29123788 | 0.83 | IDH1 (0.37) | MAPTLTA4HIDH1SCN9ASCN10A | |
| SCHEMBL30731695 | 0.80 | LTA4H (0.45) | MAPTFFAR1LTA4HTP53SMN1; SMN2 | |
| SCHEMBL29123579 | 0.80 | LTA4H (0.45) | MAPTFFAR1LTA4HTP53SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117015537-A | Heteroaryl aminopropanol derivatives as inhibitors of LTA4H | 诺华股份有限公司 | 2023-11-07 | — | — | CN | disclosed |