Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 3/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 5/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | LTA4H | P09960 | 2/20 | 0.37 |
| ▸ | FPR2 | P25090 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30731741 | 1.00 | SCN9A (0.39) | SCN9AFFAR1MAPTNPSR1SMN1; SMN2 | |
| SCHEMBL29123579 | 0.90 | LTA4H (0.45) | SCN9AFFAR1MAPTSMN1; SMN2LTA4H | |
| SCHEMBL30731695 | 0.90 | LTA4H (0.45) | SCN9AFFAR1MAPTSMN1; SMN2LTA4H | |
| SCHEMBL30731757 | 0.88 | MAPT (0.38) | SCN9AFFAR1MAPTSMN1; SMN2LTA4H | |
| SCHEMBL29123787 | 0.88 | MAPT (0.38) | SCN9AFFAR1MAPTSMN1; SMN2LTA4H | |
| SCHEMBL29123584 | 0.84 | LTA4H (0.43) | SCN9AFFAR1MAPTNPSR1SMN1; SMN2 | |
| SCHEMBL29123582 | 0.84 | LTA4H (0.43) | SCN9AFFAR1MAPTNPSR1SMN1; SMN2 | |
| SCHEMBL29123660 | 0.82 | SCN9A (0.37) | SCN9AFFAR1MAPTNPSR1SMN1; SMN2 | |
| SCHEMBL30731710 | 0.79 | LTA4H (0.44) | SCN9AMAPTSMN1; SMN2LTA4HFPR2 | |
| SCHEMBL29123425 | 0.79 | LTA4H (0.44) | SCN9AMAPTSMN1; SMN2LTA4HFPR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117015537-A | Heteroaryl aminopropanol derivatives as inhibitors of LTA4H | 诺华股份有限公司 | 2023-11-07 | — | — | CN | disclosed |