Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 2/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.32 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.32 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | RET | P07949 | 1/20 | 0.31 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.31 |
| ▸ | CAMK1D | Q8IU85 | 1/20 | 0.31 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2701836 | 0.81 | FFAR3 (0.54) | OPRL1SLC1A2SLC1A1FFAR3L3MBTL1 | |
| SCHEMBL663384 | 0.81 | FFAR3 (0.54) | OPRL1SLC1A2SLC1A1FFAR3L3MBTL1 | |
| SCHEMBL5277555 | 0.79 | FFAR3 (0.31) | OPRL1FFAR3 | |
| Fluoride SCHEMBL10012083 | 0.79 | FFAR3 (0.52) | OPRL1SLC1A2SLC1A1FFAR3L3MBTL1 | |
| SCHEMBL10012078 | 0.79 | FFAR3 (0.31) | OPRL1FFAR3 | |
| SCHEMBL1468235 | 0.76 | FFAR3 (0.33) | OPRL1FFAR3 | |
| SCHEMBL2700864 | 0.76 | FFAR3 (0.33) | OPRL1FFAR3 | |
| SCHEMBL2701515 | 0.76 | FFAR3 (0.33) | OPRL1FFAR3 | |
| SCHEMBL305654 | 0.76 | TRPA1 (0.35) | OPRL1ALOX5EPHX1FFAR3L3MBTL1 | |
| SCHEMBL305655 | 0.76 | TRPA1 (0.35) | OPRL1ALOX5EPHX1FFAR3L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 439 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119930456-A | Method for preparing N-ethyl-L-menthyl formamide by continuous flow technology | 安徽科芯微流化工科技有限公司 | 2025-05-06 | — | — | CN | claimed |
| CN-119632894-A | Preparation method of gum-protecting tooth-fixing toothpaste | 杭州博济堂健康咨询管理有限公司 | 2025-03-18 | — | — | CN | claimed |
| CN-117243884-B | Composition containing fermentation active substance for improving skin barrier, preparation method and application thereof | 广州瑞誉化工科技有限公司 | 2024-04-05 | — | — | CN | claimed |
| CN-117479843-A | Composition for enhancing cooling effect | 弗门尼舍公司 | 2024-01-30 | — | — | CN | claimed |
| CN-117338631-A | Skin care lotion prepared based on bidirectional indissolvable substance microemulsifying technology and preparation method thereof | 贵州九立德生物制药有限公司 | 2024-01-05 | — | — | CN | claimed |
| CN-117243884-A | Composition containing fermentation active substance for improving skin barrier, preparation method and application thereof | 广州瑞誉化工科技有限公司 | 2023-12-19 | — | — | CN | claimed |
| WO-2023063269-A1 | NONAQUEOUS COMPOSITION FOR ORAL CAVITY | ライオン株式会社 | 2023-04-20 | — | — | WO | claimed |
| EP-2346475-B2 | PERSONAL CARE COMPOSITIONS PROVIDING ENHANCED COOLING SENSATION | PROCTER & GAMBLE (US) | 2023-04-19 | — | — | EP | claimed |
| CN-113081900-B | Gargle and preparation method and application thereof | 河北科技大学 | 2023-03-31 | — | — | CN | claimed |
| CN-113499286-B | Cleaning and nursing composition, cleaning and nursing liquid and preparation method thereof | 福建省千喜健康科技有限公司 | 2023-02-24 | — | — | CN | claimed |
| EP-2229352-A2 | CARBOXAMIDE DERIVATIVES HAVING COOLING PROPERTIES | Givaudan SA (CH) | 2010-09-22 | — | — | EP | claimed |
| EP-2167024-A2 | COOLING COMPOUNDS | Givaudan SA (CH) | 2010-03-31 | — | — | EP | claimed |
| US-20100076080-A1 | Synthesis of Cyclohexane Derivatives Useful as Sensates in Consumer Products | THE PROCTER & GAMBLE COMPANY | 2010-03-25 | — | — | US | claimed |
| WO-2010019730-A1 | SYNTHESIS OF CYCLOHEXANE DERIVATIVES USEFUL AS SENSATES IN CONSUMER PRODUCTS | THE PROCTER & GAMBLE COMPANY (US) | 2010-02-18 | — | — | WO | claimed |
| WO-2009105740-A2 | ABSORBENT ARTICLE COMPRISING LOTION COMPOSITION COMPRISING A COOLING AGENT | THE PROCTER & GAMBLE COMPANY (US) | 2009-08-27 | — | — | WO | claimed |
| WO-2009089641-A1 | BENZIMIDAZOLE DERIVATIVES AND THEIR USE AS COOLING AGENTS | GIVAUDAN SA (CH) | 2009-07-23 | — | — | WO | claimed |
| WO-2009070910-A2 | CARBOXAMIDE DERIVATIEVES HAVING COOLING PROPERTIES | GIVAUDAN SA (CH) | 2009-06-11 | — | — | WO | claimed |
| WO-2008151460-A2 | COOLING COMPOUNDS | GIVAUDAN SA (CH) | 2008-12-18 | — | — | WO | claimed |
| WO-2008049651-A1 | PERFORMANCE-ENHANCED COSMETIC COMPOSITIONS WITH PURINE AND/OR PURINE DERIVATIVES | HENKEL AG & CO. KGAA (DE) | 2008-05-02 | — | — | WO | claimed |
| EP-1880705-A2 | Brightening and/or colouring composition with improved product sensation | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2008-01-23 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100076080-A1 | Synthesis of Cyclohexane Derivatives Useful as Sensates in Consumer Products | NISCH, TRPM4, TRPM8 | OPRL1 347/4885ALOX5 715/4885TDP1 4445/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.