Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRS3 | P32247 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | STAT3 | P40763 | 1/20 | 0.34 |
| ▸ | STAT1 | P42224 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29125720 | 0.85 | HTR1A (0.38) | HTR1AADRA2AADRA2BADRA2CNPC1 | |
| SCHEMBL29125998 | 0.77 | BRS3 (0.39) | BRS3NPC1RAB9AGLATSHR | |
| SCHEMBL29125683 | 0.76 | TSHR (0.51) | BRS3NPC1RAB9ATSHRMEN1 | |
| SCHEMBL29125707 | 0.76 | RAB9A (0.55) | BRS3NPC1RAB9AALDH1A1LMNA | |
| SCHEMBL29125867 | 0.75 | ALDH1A1 (0.45) | HTR1AADRA2AADRA2BADRA2CNPC1 | |
| SCHEMBL29125830 | 0.75 | NISCH (0.49) | BRS3HTR1AADRA2AADRA2BADRA2C | |
| SCHEMBL29125928 | 0.73 | TSHR (0.49) | BRS3HTR1AADRA2AADRA2BADRA2C | |
| SCHEMBL29125822 | 0.71 | RAB9A (0.54) | NPC1RAB9ATSHRMEN1KMT2A | |
| SCHEMBL29125853 | 0.69 | DAO (0.45) | NPC1RAB9AGAAMAPT | |
| SCHEMBL29125873 | 0.69 | ALDH1A1 (0.64) | ALDH1A1TSHRMEN1GAASTAT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117247361-A | Phenol-oxazolone/thioketone compound and synthetic method and application thereof | 吉首大学 | 2023-12-19 | — | — | CN | disclosed |