Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NISCH | Q9Y2I1 | 2/20 | 0.49 |
| ▸ | BRS3 | P32247 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | PDE9A | O76083 | 1/20 | 0.41 |
| ▸ | PDE1A | P54750 | 1/20 | 0.41 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.41 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
| ▸ | ANXA2 | P07355 | 1/20 | 0.38 |
| ▸ | S100A10 | P60903 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29125971 | 0.87 | NISCH (0.48) | NISCHBRS3MAPTL3MBTL1NPSR1 | |
| SCHEMBL29125707 | 0.83 | RAB9A (0.55) | NISCHBRS3MAPTNPSR1TSHR | |
| SCHEMBL29125683 | 0.80 | TSHR (0.51) | BRS3MAPTL3MBTL1TSHRHTT | |
| SCHEMBL13793881 | 0.76 | L3MBTL1 (0.60) | NISCHMAPTL3MBTL1NPSR1TSHR | |
| SCHEMBL29125822 | 0.76 | RAB9A (0.54) | L3MBTL1TSHRHCAR2MEN1KMT2A | |
| SCHEMBL29125708 | 0.75 | BRS3 (0.39) | BRS3MAPTTSHRALDH1A1GLA | |
| SCHEMBL29125998 | 0.75 | BRS3 (0.39) | BRS3MAPTTSHRGLATP53 | |
| SCHEMBL29125895 | 0.72 | SOD1 (0.56) | L3MBTL1TSHRALDH1A1HTTHCAR2 | |
| SCHEMBL30788473 | 0.72 | SOD1 (0.56) | L3MBTL1TSHRALDH1A1HTTHCAR2 | |
| SCHEMBL9287657 | 0.72 | HCAR2 (0.47) | NISCHMAPTL3MBTL1NPSR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117247361-A | Phenol-oxazolone/thioketone compound and synthetic method and application thereof | 吉首大学 | 2023-12-19 | — | — | CN | disclosed |