Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 5/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.33 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.33 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29125974 | 0.87 | ALDH1A1 (0.46) | ALDH1A1ENPP3TP53ALOX15TSHR | |
| SCHEMBL29125920 | 0.86 | ALDH1A1 (0.40) | NOTUMMTNR1BSORT1MTNR1AALDH1A1 | |
| SCHEMBL29126017 | 0.82 | MTNR1B (0.39) | NOTUMMTNR1BSORT1MTNR1A | |
| SCHEMBL29128439 | 0.81 | — | — | |
| SCHEMBL29125754 | 0.80 | SORT1 (0.35) | NOTUMMTNR1BSORT1MTNR1AALDH1A1 | |
| SCHEMBL29126050 | 0.78 | NOTUM (0.43) | NOTUMMTNR1BSORT1MTNR1AALDH1A1 | |
| SCHEMBL29125930 | 0.76 | SORT1 (0.35) | NOTUMMTNR1BSORT1MTNR1AALDH1A1 | |
| SCHEMBL29125770 | 0.76 | RRM1 (0.35) | NOTUMMTNR1BSORT1MTNR1A | |
| SCHEMBL29125787 | 0.74 | SORT1 (0.35) | NOTUMMTNR1BSORT1MTNR1AALDH1A1 | |
| SCHEMBL29125870 | 0.73 | ALDH1A1 (0.47) | NOTUMMTNR1BMTNR1AALDH1A1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117247361-A | Phenol-oxazolone/thioketone compound and synthetic method and application thereof | 吉首大学 | 2023-12-19 | — | — | CN | disclosed |