Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | RXRA | P19793 | 1/20 | 0.41 |
| ▸ | RXRB | P28702 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 2/20 | 0.37 |
| ▸ | APOBEC3G | Q9HC16 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29125818 | 0.85 | TSHR (0.45) | SMN1; SMN2HTTLMNAPOLBRXRA | |
| SCHEMBL29125964 | 0.80 | MAOB (0.41) | SMN1; SMN2RAB9ANPC1KDM4EALDH1A1 | |
| SCHEMBL29125838 | 0.79 | MAPT (0.35) | SMN1; SMN2HTTLMNAPOLBGAA | |
| SCHEMBL29125912 | 0.79 | RAB9A (0.53) | SMN1; SMN2LMNAGAAKCNH2RAB9A | |
| SCHEMBL20782346 | 0.74 | RXRA (0.42) | SMN1; SMN2HTTLMNAPOLBGAA | |
| SCHEMBL29128201 | 0.73 | RXRA (0.41) | SMN1; SMN2HTTLMNAPOLBGAA | |
| SCHEMBL29125879 | 0.70 | SOD1 (0.49) | SMN1; SMN2HTTLMNAPOLBGAA | |
| SCHEMBL30788509 | 0.70 | SOD1 (0.49) | SMN1; SMN2HTTLMNAPOLBGAA | |
| SCHEMBL13160063 | 0.69 | RXRA (0.72) | POLBRXRARXRBRAB9ANPC1 | |
| SCHEMBL12279053 | 0.69 | RXRA (0.72) | POLBRXRARXRBRAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117247361-A | Phenol-oxazolone/thioketone compound and synthetic method and application thereof | 吉首大学 | 2023-12-19 | — | — | CN | disclosed |