Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM4 | Q14833 | 3/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 4/20 | 0.34 |
| ▸ | HTR7 | P34969 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | RAB9A | P51151 | 5/20 | 0.33 |
| ▸ | NPC1 | O15118 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29125928 | 0.86 | TSHR (0.49) | GRM4HTR1AADRA2AADRA2BADRA2C | |
| SCHEMBL29125815 | 0.81 | TSHR (0.33) | TSHRLMNAHTT | |
| SCHEMBL29125764 | 0.80 | TSHR (0.32) | GRM4HTR1AADRA2AADRA2BADRA2C | |
| SCHEMBL29125889 | 0.79 | TSHR (0.41) | TSHRLMNASMN1; SMN2MAPTKDM4E | |
| SCHEMBL29125952 | 0.77 | LMNA (0.32) | LMNAHPGDKMT2A | |
| SCHEMBL30788494 | 0.77 | LMNA (0.32) | LMNAHPGDKMT2A | |
| SCHEMBL29125759 | 0.75 | ALDH1A1 (0.39) | TSHRLMNASMN1; SMN2MAPTHPGD | |
| SCHEMBL29125720 | 0.73 | HTR1A (0.38) | GRM4HTR1AADRA2AADRA2BADRA2C | |
| SCHEMBL29125814 | 0.72 | SMN1; SMN2 (0.41) | LMNASMN1; SMN2RAB9ANPC1MAPT | |
| SCHEMBL29125694 | 0.70 | RAB9A (0.51) | TSHRLMNASMN1; SMN2RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117247361-A | Phenol-oxazolone/thioketone compound and synthetic method and application thereof | 吉首大学 | 2023-12-19 | — | — | CN | disclosed |