Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | KDM1A | O60341 | 2/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17444517 | 0.87 | NOTUM (0.36) | KDM4EMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL14713128 | 0.79 | SIGMAR1 (0.36) | KDM4EMAPTHCRTR1LMNAKDM1A | |
| SCHEMBL27212886 | 0.76 | TSHR (0.36) | ALDH1A1MEN1KMT2ALMNANOTUM | |
| SCHEMBL29127879 | 0.69 | SIGMAR1 (0.49) | KDM4EMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL29506784 | 0.69 | KMT2A (0.47) | KDM4EMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL3144433 | 0.69 | KMT2A (0.47) | KDM4EMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL20066137 | 0.68 | OPRM1 (0.54) | KDM4EMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL30666770 | 0.68 | KDM1A (0.45) | MEN1KMT2ACYP2C9KDM1AHSD11B1 | |
| Bromide SCHEMBL5405629 | 0.67 | KMT2A (0.46) | KDM4EMAPTALDH1A1MEN1KMT2A | |
| Iodide SCHEMBL3430930 | 0.67 | KMT2A (0.46) | KDM4EMAPTALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116940552-A | Spirocyclic hexane derivatives, pharmaceutical compositions containing them and their use as anti-apoptotic inhibitors | 法国施维雅药厂 | 2023-10-24 | — | — | CN | disclosed |