Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESRRB | O95718 | 1/20 | 0.47 |
| ▸ | ESR1 | P03372 | 1/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.44 |
| ▸ | MMP2 | P08253 | 2/20 | 0.43 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.43 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.42 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.42 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.41 |
| ▸ | MIF | P14174 | 4/20 | 0.40 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.40 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.40 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.40 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12240328 | 0.87 | HPGD (0.49) | MMP2ADAM17CA2CA1CA7 | |
| SCHEMBL12264721 | 0.85 | MTNR1A (0.51) | MMP2ADAM17CA2CA1CA7 | |
| SCHEMBL7862178 | 0.83 | ADRB2 (0.38) | MMP2ADAM17CA2CA12CA1 | |
| Hydrochloric Acid SCHEMBL9536911 | 0.82 | ESR1 (0.43) | ESRRBESR1ESR2MMP2CA2 | |
| SCHEMBL19876726 | 0.80 | MTNR1A (0.52) | MMP2ADAM17MTNR1AMTNR1B | |
| SCHEMBL5546946 | 0.77 | ESR1 (0.65) | ESRRBESR1ESR2CA2CA12 | |
| SCHEMBL4185343 | 0.77 | ESR1 (0.65) | ESRRBESR1ESR2CA2CA12 | |
| SCHEMBL15314148 | 0.77 | ESR1 (0.65) | ESRRBESR1ESR2CA2CA12 | |
| SCHEMBL3658991 | 0.76 | MAOA (0.42) | ESR1ESR2CA2MTNR1AMTNR1B | |
| SCHEMBL28743243 | 0.75 | MMP2 (0.42) | MMP2ADAM17MMP9MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116997546-A | APOL1 inhibitors and methods of use | 梅兹治疗公司 | 2023-11-03 | — | — | CN | disclosed |