Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 4/20 | 0.38 |
| ▸ | MITF | O75030 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | POLB | P06746 | 6/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | CXCR5 | P32302 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29128222 | 0.85 | HRH3 (0.38) | SMN1; SMN2TP53MITFRAB9ANPC1 | |
| SCHEMBL29128527 | 0.84 | HCAR2 (0.36) | SMN1; SMN2RAB9ANPC1KDM4E | |
| SCHEMBL29128546 | 0.83 | KCNA3 (0.41) | SMN1; SMN2RAB9AKDM4EGAAHRH3 | |
| SCHEMBL29128178 | 0.77 | KDM4E (0.37) | SMN1; SMN2TP53RAB9ANPC1LMNA | |
| SCHEMBL30799922 | 0.75 | RAB9A (0.42) | RAB9ALMNAKDM4EKMT2AMEN1 | |
| SCHEMBL29128490 | 0.75 | RAB9A (0.42) | RAB9ALMNAKDM4EKMT2AMEN1 | |
| SCHEMBL29128511 | 0.74 | MAPK1 (0.32) | LMNAALDH1A1 | |
| SCHEMBL29128428 | 0.74 | — | — | |
| SCHEMBL29128250 | 0.72 | CTSS (0.33) | LMNAKMT2APOLBALDH1A1USP2 | |
| SCHEMBL29128313 | 0.72 | CYP1A2 (0.32) | SMN1; SMN2LMNAKDM4EKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117263862-A | Phenol-1, 3-oxazole/dihydroimidazole-2-ketone/thioketone compound and synthesis and application thereof | 吉首大学 | 2023-12-22 | — | — | CN | disclosed |