SCHEMBL29128397

SCHEMBL29128397

O=c1[nH]cc(CSCCOc2cccc(F)c2)[nH]1

nearest known ligand 0.44

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
DAO P14920 2/20 0.44
MAOB P27338 1/20 0.41
HCAR2 Q8TDS4 1/20 0.39
KDM4E B2RXH2 1/20 0.38
MEN1 O00255 1/20 0.38
MAPK1 P28482 1/20 0.38
KMT2A Q03164 1/20 0.38
CYP1A2 P05177 1/20 0.38
CYP3A4 P08684 1/20 0.38
CYP2D6 P10635 1/20 0.38
CYP2C9 P11712 1/20 0.38
CYP2C19 P33261 1/20 0.38
DPYD Q12882 1/20 0.36
ALDH1A1 P00352 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30799972 1.00 DAO (0.44) DAOMAOBHCAR2KDM4EMEN1
SCHEMBL30799861 0.85 DAO (0.39) DAOMAOBHCAR2KDM4EMEN1
SCHEMBL29128366 0.85 DAO (0.39) DAOMAOBHCAR2KDM4EMEN1
SCHEMBL29128495 0.83 LMNA (0.50) KDM4EMAPK1DPYDALDH1A1
SCHEMBL30799962 0.83 LMNA (0.50) KDM4EMAPK1DPYDALDH1A1
SCHEMBL29128467 0.81 ADRA1D (0.34) DAOKDM4EALDH1A1
SCHEMBL29128490 0.80 RAB9A (0.42) MAOBKDM4EMEN1KMT2ACYP1A2
SCHEMBL30799922 0.80 RAB9A (0.42) MAOBKDM4EMEN1KMT2ACYP1A2
SCHEMBL30800062 0.79 CYP1A2 (0.32) KDM4EMEN1KMT2ACYP1A2CYP3A4
SCHEMBL29128313 0.79 CYP1A2 (0.32) KDM4EMEN1KMT2ACYP1A2CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117263862-A Phenol-1, 3-oxazole/dihydroimidazole-2-ketone/thioketone compound and synthesis and application thereof 吉首大学 2023-12-22 CN disclosed