SCHEMBL29128366

SCHEMBL29128366

Fc1cccc(OCCSCc2c[nH]c(=S)[nH]2)c1

nearest known ligand 0.39

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
DAO P14920 1/20 0.39
CYP1A2 P05177 1/20 0.38
CYP3A4 P08684 1/20 0.38
CYP2D6 P10635 1/20 0.38
CYP2C9 P11712 1/20 0.38
CYP2C19 P33261 1/20 0.38
ALDH1A1 P00352 2/20 0.37
MAOB P27338 3/20 0.36
KDM4E B2RXH2 2/20 0.36
HCAR2 Q8TDS4 1/20 0.35
MEN1 O00255 1/20 0.32
MAPK1 P28482 1/20 0.32
KMT2A Q03164 1/20 0.32
SLC6A2 P23975 2/20 0.31
SLC6A4 P31645 2/20 0.31
HTR1A P08908 1/20 0.31
SLC6A3 Q01959 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30799861 1.00 DAO (0.39) DAOCYP1A2CYP3A4CYP2D6CYP2C9
SCHEMBL29128397 0.85 DAO (0.44) DAOCYP1A2CYP3A4CYP2D6CYP2C9
SCHEMBL30799972 0.85 DAO (0.44) DAOCYP1A2CYP3A4CYP2D6CYP2C9
SCHEMBL29128303 0.84 ALDH1A1 (0.50) CYP1A2CYP3A4CYP2D6CYP2C9CYP2C19
SCHEMBL29128210 0.83 KDM4E (0.41) CYP1A2CYP3A4CYP2D6CYP2C9CYP2C19
SCHEMBL30800038 0.83 KDM4E (0.41) CYP1A2CYP3A4CYP2D6CYP2C9CYP2C19
SCHEMBL29128572 0.81 SLC6A4 (0.33) ALDH1A1KDM4ESLC6A4
SCHEMBL29128257 0.81 KDM4E (0.33) ALDH1A1KDM4ESLC6A4
SCHEMBL30800046 0.80 RAB9A (0.42) CYP1A2CYP3A4CYP2D6CYP2C9CYP2C19
SCHEMBL29128359 0.78 ALDH1A1 (0.43) ALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117263862-A Phenol-1, 3-oxazole/dihydroimidazole-2-ketone/thioketone compound and synthesis and application thereof 吉首大学 2023-12-22 CN disclosed