Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 5/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | OGG1 | O15527 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | RHEB | Q15382 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29128371 | 0.86 | LMNA (0.36) | TP53LMNATHRBSLC6A4CYP3A4 | |
| SCHEMBL29128343 | 0.77 | ENPP3 (0.31) | — | |
| SCHEMBL29128169 | 0.75 | ALDH1A1 (0.36) | SLC6A4CYP3A4CYP2D6CYP1A2CYP2C9 | |
| SCHEMBL29128513 | 0.74 | MAPT (0.42) | SLC6A4CYP3A4CYP2D6CYP1A2CYP2C9 | |
| SCHEMBL29128275 | 0.73 | SOD1 (0.33) | LMNACYP3A4CYP2C9CYP2C19POLB | |
| SCHEMBL29128247 | 0.73 | ALDH1A1 (0.37) | LMNACYP2D6ALDH1A1KMT2A | |
| SCHEMBL29128416 | 0.71 | ALDH1A1 (0.33) | ALDH1A1 | |
| SCHEMBL29128188 | 0.71 | ALDH1A1 (0.32) | SLC6A4ALDH1A1 | |
| SCHEMBL29128442 | 0.68 | ALDH1A1 (0.47) | TP53LMNACYP3A4CYP2D6CYP1A2 | |
| SCHEMBL29128238 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117263862-A | Phenol-1, 3-oxazole/dihydroimidazole-2-ketone/thioketone compound and synthesis and application thereof | 吉首大学 | 2023-12-22 | — | — | CN | disclosed |