Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 7/20 | 0.48 |
| ▸ | UCHL1 | P09936 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL356138 | 0.86 | SCN4A (0.45) | USP30UCHL1ALDH1A1KMT2ATSHR | |
| SCHEMBL8215613 | 0.86 | SCN4A (0.45) | USP30UCHL1ALDH1A1KMT2ATSHR | |
| SCHEMBL8240664 | 0.86 | SCN4A (0.45) | USP30UCHL1ALDH1A1KMT2ATSHR | |
| SCHEMBL8218887 | 0.84 | ADAM17 (0.46) | USP30UCHL1ALDH1A1KMT2ATSHR | |
| SCHEMBL8222820 | 0.82 | USP30 (0.51) | USP30UCHL1ALDH1A1TSHRL3MBTL1 | |
| SCHEMBL8221844 | 0.82 | USP30 (0.52) | USP30UCHL1ALDH1A1KMT2ATSHR | |
| SCHEMBL6468249 | 0.81 | HSD11B1 (0.45) | USP30UCHL1ALDH1A1KMT2ATSHR | |
| SCHEMBL8222445 | 0.80 | USP30 (0.56) | USP30UCHL1ALDH1A1KMT2ATSHR | |
| SCHEMBL30912450 | 0.79 | UCHL1 (0.49) | USP30UCHL1ALDH1A1KMT2ATSHR | |
| SCHEMBL30912508 | 0.79 | UCHL1 (0.49) | USP30UCHL1ALDH1A1KMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117279896-A | Amino substituted pyrido ring compounds, preparation method and application thereof | 劲方医药科技(上海)有限公司 | 2023-12-22 | — | — | CN | disclosed |
| WO-2022214044-A1 | AMINE-SUBSTITUTED PYRIDINE FUSED RING COMPOUNDS, PREPARATION METHOD THEREFOR AND USE THEREOF | 劲方医药科技(上海)有限公司 | 2022-10-13 | — | — | WO | disclosed |