SCHEMBL29129663

SCHEMBL29129663

CCc1ccccc1-c1cc(=O)c2cc(O)c(OC)cc2o1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 5/20 0.68
ALDH1A1 P00352 5/20 0.68
KDM4E B2RXH2 4/20 0.68
TP53 P04637 4/20 0.68
HSD17B10 Q99714 3/20 0.68
CYP2D6 P10635 3/20 0.68
HPGD P15428 7/20 0.57
CYP3A4 P08684 4/20 0.57
TSHR P16473 2/20 0.57
CYP2C9 P11712 3/20 0.53
AR P10275 1/20 0.52
CSNK2A2 P19784 5/20 0.52
CSNK2B P67870 5/20 0.52
CSNK2A1 P68400 5/20 0.52
MEN1 O00255 4/20 0.51
KMT2A Q03164 4/20 0.51
MAPT P10636 4/20 0.51
SMN1; SMN2 Q16637 4/20 0.51
MAPK1 P28482 3/20 0.51
POLB P06746 2/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27883079 0.90 ALDH1A1 (0.65) CYP2C19ALDH1A1KDM4ETP53HSD17B10
SCHEMBL29129658 0.87 HPGD (0.61) CYP2C19ALDH1A1KDM4ETP53HSD17B10
SCHEMBL29169304 0.83 CYP2C19 (0.67) CYP2C19ALDH1A1KDM4ETP53HSD17B10
SCHEMBL4648917 0.81 KDM4E (1.00) CYP2C19ALDH1A1KDM4ETP53HSD17B10
SCHEMBL28292483 0.80 AKR1C3 (0.59) CYP2C19ALDH1A1KDM4ETP53HSD17B10
SCHEMBL29128894 0.79 AR (0.73) CYP2C19ALDH1A1KDM4ETP53HSD17B10
SCHEMBL27806529 0.79 HPGD (0.67) CYP2C19ALDH1A1KDM4ETP53HPGD
SCHEMBL28182849 0.77 ALDH1A1 (0.65) CYP2C19ALDH1A1KDM4ETP53HSD17B10
SCHEMBL11035644 0.76 HPGD (0.63) CYP2C19ALDH1A1KDM4ETP53HSD17B10
SCHEMBL13730323 0.76 KDM4E (0.90) CYP2C19ALDH1A1KDM4ETP53HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117250298-A Construction method of liquid fingerprint of agilawood and fingerprint thereof 中国中医科学院中药研究所 2023-12-19 CN claimed
CN-117250298-A Construction method of liquid fingerprint of agilawood and fingerprint thereof 中国中医科学院中药研究所 2023-12-19 CN disclosed