Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.55 |
| ▸ | GAA | P10253 | 3/20 | 0.55 |
| ▸ | RECQL | P46063 | 2/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | INPPL1 | O15357 | 1/20 | 0.55 |
| ▸ | ALPL | P05186 | 1/20 | 0.55 |
| ▸ | ALPI | P09923 | 1/20 | 0.55 |
| ▸ | ALPG | P10696 | 1/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
| ▸ | APEX1 | P27695 | 1/20 | 0.55 |
| ▸ | BLM | P54132 | 1/20 | 0.55 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.55 |
| ▸ | PFKFB3 | Q16875 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | CDK1 | P06493 | 5/20 | 0.50 |
| ▸ | CCNB1 | P14635 | 5/20 | 0.50 |
| ▸ | ACHE | P22303 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27997244 | 0.84 | MAPT (0.54) | MAPTKMT2AKDM4EGAARECQL | |
| SCHEMBL28058613 | 0.82 | CYP1A1 (0.50) | MAPTKMT2AKDM4EGAARECQL | |
| SCHEMBL28666571 | 0.82 | KMT2A (0.64) | MAPTKMT2AKDM4EGAARECQL | |
| SCHEMBL27974348 | 0.77 | MAPT (0.77) | MAPTKMT2AKDM4EGAARECQL | |
| SCHEMBL3190273 | 0.74 | KMT2A (0.58) | MAPTKMT2AKDM4EGAARECQL | |
| SCHEMBL29129658 | 0.73 | HPGD (0.61) | MAPTKMT2AKDM4EGAARECQL | |
| SCHEMBL8105644 | 0.73 | MAPKAPK2 (0.46) | MAPTKMT2ATDP1POLBALDH1A1 | |
| SCHEMBL27806529 | 0.72 | HPGD (0.67) | MAPTKMT2AKDM4ERECQLPOLB | |
| SCHEMBL11035644 | 0.72 | HPGD (0.63) | MAPTKMT2AKDM4EGAARECQL | |
| SCHEMBL27775457 | 0.71 | ALDH1A1 (0.65) | MAPTKMT2AKDM4EGAARECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117137981-A | Activation of AMPK by agilawood extract | 中国中医科学院中药研究所 | 2023-12-01 | — | — | CN | claimed |
| CN-117018091-A | Activation of AMPK by Phoebe cheilis extract | 中国中医科学院中药研究所 | 2023-11-10 | — | — | CN | claimed |
| CN-117250298-A | Construction method of liquid fingerprint of agilawood and fingerprint thereof | 中国中医科学院中药研究所 | 2023-12-19 | — | — | CN | disclosed |
| CN-117137981-A | Activation of AMPK by agilawood extract | 中国中医科学院中药研究所 | 2023-12-01 | — | — | CN | disclosed |
| CN-117017972-A | Activation of AMPK by lignum Aquilariae Resinatum component | 中国中医科学院中药研究所 | 2023-11-10 | — | — | CN | disclosed |
| CN-117018091-A | Activation of AMPK by Phoebe cheilis extract | 中国中医科学院中药研究所 | 2023-11-10 | — | — | CN | disclosed |