Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 6/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 5/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | DPP4 | P27487 | 2/20 | 0.41 |
| ▸ | CDK2 | P24941 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2913408 | 0.88 | GSK3B (0.43) | GSK3BMAPTALDH1A1NPC1GAA | |
| SCHEMBL2909845 | 0.86 | GSK3B (0.42) | GSK3BMAPTALDH1A1NPC1GAA | |
| SCHEMBL2910724 | 0.86 | GSK3B (0.42) | GSK3BMAPTALDH1A1NPC1GAA | |
| SCHEMBL2913237 | 0.86 | GSK3B (0.42) | GSK3BMAPTALDH1A1NPC1GAA | |
| SCHEMBL2912944 | 0.86 | GSK3B (0.42) | GSK3BMAPTALDH1A1NPC1GAA | |
| SCHEMBL2909838 | 0.83 | GSK3B (0.47) | GSK3BMAPTALDH1A1NPC1GAA | |
| SCHEMBL2912436 | 0.83 | F10 (0.41) | GSK3B | |
| SCHEMBL2909840 | 0.83 | GSK3B (0.55) | GSK3BDPP4CDK2 | |
| SCHEMBL1219415 | 0.83 | GSK3B (0.51) | GSK3BMAPTALDH1A1CDK2LMNA | |
| SCHEMBL2912175 | 0.80 | GSK3B (0.51) | GSK3BMAPTALDH1A1CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1537099-B1 | PYRROLE BASED INHIBITORS OF GLYCOGEN SYNTHASE KINASE 3 | NOVARTIS VACCINES & DIAGNOSTIC (US) | 2010-08-11 | — | — | EP | disclosed |