Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 1/20 | 0.41 |
| ▸ | PPARD | Q03181 | 1/20 | 0.41 |
| ▸ | HCRTR1 | O43613 | 4/20 | 0.40 |
| ▸ | GCGR | P47871 | 5/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.38 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.38 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.38 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.38 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.38 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.38 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.38 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.38 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.38 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2909829 | 0.88 | HCRTR1 (0.41) | F10PPARDHCRTR1GCGRCNR1 | |
| SCHEMBL2910207 | 0.86 | ALOX5AP (0.40) | F10PPARDHCRTR1GCGRCNR1 | |
| SCHEMBL2904248 | 0.86 | PPARD (0.41) | F10PPARDHCRTR1GCGRCNR1 | |
| SCHEMBL2904288 | 0.86 | PPARD (0.41) | F10PPARDHCRTR1GCGRCNR1 | |
| SCHEMBL2911026 | 0.86 | ALOX5AP (0.40) | F10PPARDHCRTR1GCGRCNR1 | |
| SCHEMBL2909840 | 0.84 | GSK3B (0.55) | GSK3B | |
| SCHEMBL2912974 | 0.83 | GSK3B (0.47) | GSK3B | |
| SCHEMBL1219415 | 0.75 | GSK3B (0.51) | GSK3B | |
| SCHEMBL2913408 | 0.73 | GSK3B (0.43) | GSK3BCNR1 | |
| SCHEMBL3261753 | 0.73 | ALDH1A1 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1537099-B1 | PYRROLE BASED INHIBITORS OF GLYCOGEN SYNTHASE KINASE 3 | NOVARTIS VACCINES & DIAGNOSTIC (US) | 2010-08-11 | — | — | EP | disclosed |