Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 14/20 | 0.47 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.42 |
| ▸ | F2 | P00734 | 1/20 | 0.42 |
| ▸ | F10 | P00742 | 1/20 | 0.42 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.40 |
| ▸ | SMO | Q99835 | 1/20 | 0.40 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28039302 | 0.81 | TGFBR1 (0.46) | FFAR1PDK1RIPK2POLB | |
| SCHEMBL21177151 | 0.78 | KARS1 (0.43) | FFAR1PDK1RIPK2POLBNTRK1 | |
| SCHEMBL7656159 | 0.75 | IDO1 (0.59) | POLB | |
| SCHEMBL5868830 | 0.74 | JMJD6 (0.53) | RIPK2POLB | |
| SCHEMBL29059534 | 0.74 | PRKCI (0.57) | FFAR1 | |
| SCHEMBL14412223 | 0.74 | NMT1 (0.52) | F2F10RIPK2NTRK1 | |
| SCHEMBL29711750 | 0.73 | HSD17B2 (0.48) | PDK1RIPK2NTRK1 | |
| SCHEMBL18641295 | 0.73 | AGXT (0.61) | FFAR1POLB | |
| SCHEMBL2616608 | 0.73 | HSD17B2 (0.48) | PDK1RIPK2NTRK1 | |
| SCHEMBL9677464 | 0.72 | LMNA (0.48) | F2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117069728-A | PI4KIII beta inhibitors | 葛兰素史克知识产权开发有限公司 | 2023-11-17 | — | — | CN | disclosed |