Tetrabuthylammonium

Tetrabuthylammonium

SCHEMBL29130243

CCCC[N+](CCCC)(CCCC)CCCC.O=S(=O)(O)O.OCCc1ccc(F)cc1

nearest known ligand 0.45

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

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

The experimentally established mechanism targets of Tetrabuthylammonium. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 1/20 0.45
FFAR4 Q5NUL3 1/20 0.45
PSMD14 O00487 1/20 0.43
HSP90AA1 P07900 1/20 0.43
MMP2 P08253 1/20 0.43
MC4R P32245 1/20 0.43
RAD52 P43351 1/20 0.43
ALDH1A1 P00352 3/20 0.41
CA2 P00918 3/20 0.40
HPGD P15428 3/20 0.39
KCNH2 Q12809 2/20 0.39
CA12 O43570 1/20 0.39
CA1 P00915 1/20 0.39
CA4 P22748 1/20 0.39
CA6 P23280 1/20 0.39
CA5A P35218 1/20 0.39
CA7 P43166 1/20 0.39
CA9 Q16790 1/20 0.39
CA14 Q9ULX7 1/20 0.39
CA5B Q9Y2D0 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Tetrabuthylammonium SCHEMBL29130249 0.83 BMP1 (0.43) ALDH1A1CA2HPGDCA12CA1
Tetrabuthylammonium SCHEMBL29130230 0.82 TSHR (0.51) FFAR1FFAR4MMP2ALDH1A1CA2
Tetrabuthylammonium SCHEMBL29130234 0.81 TSHR (0.60) ALDH1A1CA2KCNH2CA12CA1
SCHEMBL11149628 0.79 KCNH2 (0.59) FFAR1FFAR4PSMD14HSP90AA1MMP2
SCHEMBL4228481 0.79 CA2 (0.50) FFAR1FFAR4ALDH1A1CA2HPGD
Tetrabuthylammonium SCHEMBL29130269 0.78 FAAH (0.36) PSMD14HSP90AA1MMP2MC4RRAD52
Tetrabuthylammonium SCHEMBL30363487 0.77 FFAR1 (0.46) FFAR1FFAR4PSMD14HSP90AA1MMP2
Tetrabuthylammonium SCHEMBL29130236 0.75 TSHR (0.50) FFAR1FFAR4ALDH1A1CA2KCNH2
SCHEMBL11133493 0.73 KCNH2 (0.60) FFAR1FFAR4PSMD14HSP90AA1MMP2
Tetrabuthylammonium SCHEMBL243899 0.73 SLC22A1 (0.67) ALDH1A1CA2CA1HSD17B10TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117164505-A Method for synthesizing organic sulfate by dialkyl sulfate or pyrosulfate 湖南大学 2023-12-05 CN disclosed