SCHEMBL2913063

SCHEMBL2913063

CCOC(=O)c1cc(C=O)[nH]c1C

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.61
MAPT P10636 3/20 0.61
LMNA P02545 1/20 0.61
L3MBTL1 Q9Y468 1/20 0.61
GAA P10253 3/20 0.56
POLB P06746 2/20 0.56
NPC1 O15118 1/20 0.56
SMN1; SMN2 Q16637 1/20 0.54
KMT2A Q03164 4/20 0.51
KDM4E B2RXH2 1/20 0.51
MEN1 O00255 2/20 0.51
RXFP1 Q9HBX9 1/20 0.51
PDE3B Q13370 2/20 0.49
PDE3A Q14432 2/20 0.49
TSHR P16473 1/20 0.46
USP2 O75604 1/20 0.44
CYP3A4 P08684 1/20 0.44
ALOX15 P16050 1/20 0.44
HPGD P15428 1/20 0.44
CA12 O43570 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25296768 0.83 MAPT (0.49) ALDH1A1MAPTLMNAL3MBTL1GAA
SCHEMBL12672147 0.81 SMN1; SMN2 (0.45) ALDH1A1MAPTLMNAL3MBTL1GAA
SCHEMBL2921786 0.81 ALDH1A1 (0.55) ALDH1A1MAPTLMNAL3MBTL1GAA
SCHEMBL2921790 0.81 ALDH1A1 (0.55) ALDH1A1MAPTLMNAL3MBTL1GAA
SCHEMBL10747580 0.79 ALDH1A1 (0.69) ALDH1A1MAPTLMNAL3MBTL1GAA
SCHEMBL11647465 0.77 ALDH1A1 (0.67) ALDH1A1MAPTLMNAL3MBTL1GAA
SCHEMBL23732252 0.77 ALDH1A1 (0.67) ALDH1A1MAPTLMNAL3MBTL1GAA
SCHEMBL94723 0.77 ALDH1A1 (0.50) ALDH1A1MAPTLMNAL3MBTL1GAA
SCHEMBL1157003 0.76 MAPT (0.65) ALDH1A1MAPTLMNAL3MBTL1GAA
SCHEMBL9671945 0.76 ALDH1A1 (1.00) ALDH1A1MAPTLMNAL3MBTL1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250089549-A1 OPTICAL FILM, COMPOSITION FOR FORMING COLORED LAYER, DIPYRROMETHENE COBALT COMPLEX AND DISPLAY DEVICE TOPPAN HOLDINGS INC. (JP) 2025-03-13 US disclosed
EP-4462164-A1 OPTICAL FILM, COMPOSITION FOR COLORED LAYER FORMATION, DIPYRROMETHENE COBALT COMPLEX, AND DISPLAY DEVICE Toppan Holdings Inc. (JP) 2024-11-13 EP disclosed
CN-118511098-A Optical film, composition for forming colored layer, dipyrromethene cobalt complex, and display device 凸版控股株式会社 2024-08-16 CN disclosed
WO-2023132318-A1 OPTICAL FILM, COMPOSITION FOR COLORED LAYER FORMATION, DIPYRROMETHENE COBALT COMPLEX, AND DISPLAY DEVICE 凸版印刷株式会社 2023-07-13 WO disclosed
US-7855288-B2 Pyrrolo [1,2-d] [1,2-4] triazine as inhibitors of c-Jun N terminal kinases (JNK) and p-38 kinases NOVARTIS AG (CH) 2010-12-21 US disclosed
EP-1807431-B1 PYRROLO[1,2-D][1,2-4]TRIAZINE AS INHIBITORS OF C-JUN N-TERMINAL KINASES (JNK) AND P-38 KINASES NOVARTIS AG (CH) 2010-09-08 EP disclosed
US-20080253988-A1 Pyrrolo [1,2-D] [1,2-4] Triazine as Inhibitors of C-Jun N Terminal Kinases (Jnk) and P-38 Kinases NOVARTIS AG (CH) 2008-10-16 US disclosed
EP-1807431-A1 PYRROLO[1,2-D][1,2-4]TRIAZINE AS INHIBITORS OF C-JUN N-TERMINAL KINASES (JNK) AND P-38 KINASES Novartis AG (CH) 2007-07-18 EP disclosed
WO-2006047354-A1 PYRROLO [1,2-D][1,2-4]TRIAZINE AS INHIBITORS OF C-JUN N TERMINAL KINASES (JNK) AND P-38 KINASES NOVARTIS AG (CH) 2006-05-04 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080253988-A1 Pyrrolo [1,2-D] [1,2-4] Triazine as Inhibitors of C-Jun N Terminal Kinases (Jnk) and P-38 Kinases MAPK8, MAP3K8, STK38 ALDH1A1 3728/4885MAPT 1212/4885LMNA 2697/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.