Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | FABP3 | P05413 | 6/20 | 0.44 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.44 |
| ▸ | FABP4 | P15090 | 4/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.40 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | PPARD | Q03181 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.39 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.39 |
| ▸ | SNCA | P37840 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2909825 | 0.85 | ALDH1A1 (0.41) | PTGDR2PDCD1CD274ALDH1A1HPGD | |
| SCHEMBL2913115 | 0.83 | ALDH1A1 (0.40) | PTGDR2PDCD1CD274ALDH1A1HPGD | |
| SCHEMBL13140089 | 0.79 | RARB (0.40) | PTGDR2PDCD1CD274ALDH1A1HPGD | |
| SCHEMBL4266947 | 0.77 | PTGDR2 (0.50) | TSHRPTGDR2S1PR5PPARGPPARD | |
| SCHEMBL13117586 | 0.76 | FFAR1 (0.38) | TSHRPTGDR2PDCD1CD274ALDH1A1 | |
| SCHEMBL13117607 | 0.75 | SMN1; SMN2 (0.37) | PTGDR2PPARDPDCD1CD274ALDH1A1 | |
| SCHEMBL5304037 | 0.74 | PTGDR2 (0.70) | TSHRFABP3PTGDR2FABP4FFAR4 | |
| SCHEMBL13139833 | 0.72 | ERN1 (0.45) | TSHRPDCD1CD274ALDH1A1HPGD | |
| SCHEMBL10374308 | 0.72 | PTGDR2 (0.54) | TSHRPTGDR2FFAR4PPARAALDH1A1 | |
| SCHEMBL7082490 | 0.72 | FFAR4 (0.50) | TSHRFABP3PTGDR2FFAR4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100267775-A1 | OXADIAZOLIDINEDIONE COMPOUND | ASTELLAS PHARMA INC. (JP) | 2010-10-21 | — | — | US | disclosed |
| EP-2216330-A1 | OXADIAZOLIDINEDIONE COMPOUND | Astellas Pharma Inc. (JP) | 2010-08-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100267775-A1 | OXADIAZOLIDINEDIONE COMPOUND | GPR119, GLP1R, GPR4 | TSHR 877/4885FABP3 3112/4885PTGDR2 624/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.