Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMAD3 | P84022 | 1/20 | 0.51 |
| ▸ | FLT3 | P36888 | 8/20 | 0.49 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.49 |
| ▸ | ABL1 | P00519 | 1/20 | 0.49 |
| ▸ | KIT | P10721 | 1/20 | 0.49 |
| ▸ | BCR | P11274 | 1/20 | 0.49 |
| ▸ | BACE1 | P56817 | 1/20 | 0.45 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.43 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CLK1 | P49759 | 1/20 | 0.41 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.41 |
| ▸ | KDM6B | O15054 | 1/20 | 0.41 |
| ▸ | PYGL | P06737 | 1/20 | 0.39 |
| ▸ | SRC | P12931 | 1/20 | 0.39 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11230483 | 1.00 | SMAD3 (0.51) | SMAD3FLT3PDGFRBABL1KIT | |
| SCHEMBL1331747 | 0.88 | CA2 (0.42) | SMAD3FLT3CA2KDM6BADAMTS4 | |
| SCHEMBL9900757 | 0.84 | ALOX15 (0.53) | SMAD3FLT3PDGFRBABL1KIT | |
| SCHEMBL29409510 | 0.84 | ALOX15 (0.53) | SMAD3FLT3PDGFRBABL1KIT | |
| SCHEMBL29131170 | 0.83 | FLT3 (0.44) | SMAD3FLT3PDGFRBABL1KIT | |
| SCHEMBL30718327 | 0.83 | FLT3 (0.44) | SMAD3FLT3PDGFRBABL1KIT | |
| SCHEMBL5172404 | 0.81 | ADAMTS4 (0.55) | FLT3ADAMTS4KDM4EALDH1A1MAPT | |
| SCHEMBL1332798 | 0.81 | ADAMTS4 (0.55) | FLT3ADAMTS4KDM4EALDH1A1MAPT | |
| SCHEMBL29396939 | 0.81 | ADAMTS4 (0.55) | FLT3ADAMTS4KDM4EALDH1A1MAPT | |
| SCHEMBL29379275 | 0.81 | ADAMTS4 (0.55) | FLT3ADAMTS4KDM4EALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117342953-A | Use of rosmarinic acid and analogues thereof in the treatment of vascular diseases | 西北大学 | 2024-01-05 | — | — | CN | disclosed |
| CN-117304022-A | Method for synthesizing rosmarinic acid and analogues thereof | 西北大学 | 2023-12-29 | — | — | CN | disclosed |