Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 3/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.53 |
| ▸ | HTR2A | P28223 | 2/20 | 0.53 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | HTR1A | P08908 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | HTR2C | P28335 | 1/20 | 0.53 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.53 |
| ▸ | HTR7 | P34969 | 1/20 | 0.53 |
| ▸ | HTR2B | P41595 | 1/20 | 0.53 |
| ▸ | MTOR | P42345 | 1/20 | 0.53 |
| ▸ | BLM | P54132 | 1/20 | 0.53 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29409510 | 1.00 | ALOX15 (0.53) | ALOX15HSD17B10CYP3A4KDM4EADORA3 | |
| SCHEMBL11032486 | 0.84 | KDM4E (0.51) | HSD17B10KDM4ENFKB1ALDH1A1LMNA | |
| SCHEMBL454982 | 0.84 | PYGL (0.43) | ALOX15HSD17B10CYP3A4KDM4EADORA3 | |
| SCHEMBL11033505 | 0.84 | SIRT1 (0.61) | CYP3A4KMT2AEGFRSIRT1CYP2C9 | |
| SCHEMBL454981 | 0.84 | PYGL (0.43) | ALOX15HSD17B10CYP3A4KDM4EADORA3 | |
| SCHEMBL11230483 | 0.84 | SMAD3 (0.51) | ALOX15HSD17B10CYP3A4KDM4EADORA3 | |
| SCHEMBL29131165 | 0.84 | SMAD3 (0.51) | ALOX15HSD17B10CYP3A4KDM4EADORA3 | |
| SCHEMBL45382 | 0.82 | ALPI (0.54) | HSD17B10KDM4EALDH1A1LMNAMAPT | |
| SCHEMBL4393088 | 0.82 | ALPI (0.54) | HSD17B10KDM4EALDH1A1LMNAMAPT | |
| SCHEMBL29440959 | 0.82 | ALPI (0.54) | HSD17B10KDM4EALDH1A1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114134186-B | Method for synthesizing 5-hydroxy beta-indolylalanine by using glucose as substrate biological method | 河北维达康生物科技有限公司 | 2025-04-22 | — | — | CN | claimed |
| CN-114672525-B | Biosynthesis method and application of N-acetyl-5-methoxy tryptamine | 河北维达康生物科技有限公司 | 2024-08-09 | — | — | CN | claimed |
| CN-116751696-A | Yarrowia lipolytica engineering bacterium for biosynthesis of 5-hydroxy beta-indolylalanine, construction and application thereof | 河北维达康生物科技有限公司 | 2023-09-15 | — | — | CN | claimed |
| CN-114875087-B | Method for synthesizing 5-hydroxy beta-indolylalanine by taking beta-indolylalanine as substrate and application thereof | 河北维达康生物科技有限公司 | 2023-08-04 | — | — | CN | claimed |
| CN-114875087-A | Method for synthesizing 5-hydroxy beta-indolyl alanine by using beta-indolyl alanine as substrate and application thereof | 河北维达康生物科技有限公司 | 2022-08-09 | — | — | CN | claimed |
| CN-114672525-A | Biosynthesis method and application of N-acetyl-5-methoxytryptamine | 河北维达康生物科技有限公司 | 2022-06-28 | — | — | CN | claimed |
| CN-114150027-A | Method for synthesizing N-acetyl-5-methoxytryptamine by using 5-hydroxy beta-indolylalanine as substrate through biological method | 河北维达康生物科技有限公司 | 2022-03-08 | — | — | CN | claimed |
| CN-114134186-A | Method for synthesizing 5-hydroxy beta-indolyl alanine by using glucose as substrate through biological method | 河北维达康生物科技有限公司 | 2022-03-04 | — | — | CN | claimed |
| CN-114150027-B | Biological method for synthesizing N-acetyl-5-methoxy tryptamine by using 5-hydroxy beta-indolylalanine as substrate | 河北维达康生物科技有限公司 | 2025-10-10 | — | — | CN | disclosed |
| CN-114150027-B | Biological method for synthesizing N-acetyl-5-methoxy tryptamine by using 5-hydroxy beta-indolylalanine as substrate | 河北维达康生物科技有限公司 | 2025-10-10 | — | — | CN | disclosed |
| CN-119899144-A | 5-Hydroxytryptophan crystal form and preparation method and application thereof | 伊犁川宁生物技术股份有限公司 | 2025-04-29 | — | — | CN | disclosed |
| CN-114134186-B | Method for synthesizing 5-hydroxy beta-indolylalanine by using glucose as substrate biological method | 河北维达康生物科技有限公司 | 2025-04-22 | — | — | CN | disclosed |
| CN-114134186-B | Method for synthesizing 5-hydroxy beta-indolylalanine by using glucose as substrate biological method | 河北维达康生物科技有限公司 | 2025-04-22 | — | — | CN | disclosed |
| CN-114134186-B | Method for synthesizing 5-hydroxy beta-indolylalanine by using glucose as substrate biological method | 河北维达康生物科技有限公司 | 2025-04-22 | — | — | CN | disclosed |
| CN-114134186-A | Method for synthesizing 5-hydroxy beta-indolyl alanine by using glucose as substrate through biological method | 河北维达康生物科技有限公司 | 2022-03-04 | — | — | CN | disclosed |
| CN-114134186-A | Method for synthesizing 5-hydroxy beta-indolyl alanine by using glucose as substrate through biological method | 河北维达康生物科技有限公司 | 2022-03-04 | — | — | CN | disclosed |
| CN-113549588-A | Genetically engineered bacterium for producing 5-hydroxytryptophan and construction method and application thereof | 天津科技大学 | 2021-10-26 | — | — | CN | disclosed |
| CN-113373103-A | Method for improving yield of 5-hydroxytryptophan | 天津科技大学 | 2021-09-10 | — | — | CN | disclosed |
| CN-112708589-A | Genetically engineered bacterium, construction method thereof and application of genetically engineered bacterium in fermentation production of 5-hydroxytryptophan | 南京工业大学 | 2021-04-27 | — | — | CN | disclosed |
| WO-2012076916-A1 | THERAPEUTIC ASSOCIATION OF 5 - HYDROXY - TRYPTOPHAN AND CAFFEINE FOR THE TREATMENT OF THE SYMPTOM OF PARKINSON'S DISEASE, DAYTIME SLEEPINESS | BRAINET DISCOVERY SRL (IT) | 2012-06-14 | — | — | WO | disclosed |