Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.37 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.33 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.33 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 4/20 | 0.31 |
| ▸ | TP53 | P04637 | 2/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL19971073 | 0.88 | HCAR2 (0.36) | LMNAALDH1A1HCAR2KEAP1NFE2L2 | |
| Bicarbonate SCHEMBL31145089 | 0.86 | LMNA (0.50) | LMNAALDH1A1CA1CA2CA9 | |
| Bicarbonate SCHEMBL27782738 | 0.86 | LMNA (0.50) | LMNAALDH1A1CA1CA2CA9 | |
| Bicarbonate SCHEMBL23522320 | 0.86 | LMNA (0.50) | LMNAALDH1A1CA1CA2CA9 | |
| Bicarbonate SCHEMBL33932 | 0.86 | — | — | |
| Bicarbonate SCHEMBL25188386 | 0.86 | LMNA (0.50) | LMNAALDH1A1CA1CA2CA9 | |
| Bicarbonate SCHEMBL16395668 | 0.85 | HCAR2 (0.35) | LMNAALDH1A1HCAR2KEAP1NFE2L2 | |
| SCHEMBL25259881 | 0.84 | — | — | |
| Bicarbonate SCHEMBL28800487 | 0.83 | LMNA (0.41) | LMNAALDH1A1HCAR2KEAP1NFE2L2 | |
| Bicarbonate SCHEMBL26109288 | 0.83 | LMNA (0.41) | LMNAALDH1A1CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115732754-B | Solid polymer electrolyte and preparation method of battery thereof | 南开大学 | 2024-03-19 | — | — | CN | claimed |
| CN-117304467-B | Fluorinated crosslinked polymer solid electrolyte, solid battery and preparation method thereof | 南开大学 | 2024-03-22 | — | — | CN | disclosed |
| CN-115732754-B | Solid polymer electrolyte and preparation method of battery thereof | 南开大学 | 2024-03-19 | — | — | CN | disclosed |
| CN-117304467-A | Fluorinated crosslinked polymer solid electrolyte, solid battery and preparation method thereof | 南开大学 | 2023-12-29 | — | — | CN | disclosed |