Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.36 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.36 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25259881 | 0.97 | — | — | |
| Bicarbonate SCHEMBL29131247 | 0.88 | LMNA (0.39) | HCAR2KEAP1NFE2L2ALDH1A1LMNA | |
| Bicarbonate SCHEMBL16395668 | 0.86 | HCAR2 (0.35) | HCAR2KEAP1NFE2L2ALDH1A1LMNA | |
| Propene SCHEMBL2938683 | 0.81 | — | — | |
| Bicarbonate SCHEMBL28053231 | 0.81 | ALDH1A1 (0.44) | HCAR2KEAP1NFE2L2ALDH1A1TSHR | |
| Bicarbonate SCHEMBL31145089 | 0.80 | LMNA (0.50) | ALDH1A1LMNATSHR | |
| Bicarbonate SCHEMBL28781234 | 0.80 | ALDH1A1 (0.50) | HCAR2KEAP1NFE2L2ALDH1A1TSHR | |
| Bicarbonate SCHEMBL23522320 | 0.80 | LMNA (0.50) | ALDH1A1LMNATSHR | |
| Bicarbonate SCHEMBL25188386 | 0.80 | LMNA (0.50) | ALDH1A1LMNATSHR | |
| Bicarbonate SCHEMBL33932 | 0.80 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12021227-B2 | Electroactive materials for metal-ion batteries | NEXEON LIMITED (GB) | 2024-06-25 | — | — | US | disclosed |
| EP-3638622-B1 | ELECTROACTIVE MATERIALS FOR METAL-ION BATTERIES | NEXEON LTD (GB) | 2024-05-22 | — | — | EP | disclosed |
| US-11923544-B2 | Surface modification | NEXEON LIMITED (GB) | 2024-03-05 | — | — | US | disclosed |
| US-11905593-B2 | Process for preparing electroactive materials for metal-ion batteries | NEXEON LIMITED (GB) | 2024-02-20 | — | — | US | disclosed |
| US-20230327078-A1 | ELECTROACTIVE MATERIALS FOR METAL-ION BATTERIES | NEXEON LIMITED (GB) | 2023-10-12 | — | — | US | disclosed |
| US-11710819-B2 | Electroactive materials for metal-ion batteries | NEXEON LIMITED (GB) | 2023-07-25 | — | — | US | disclosed |
| US-20230216058-A1 | HIGHLY EFFICIENT ELECTRODES ENABLED BY SEGREGATED NETWORKS | THE PROVOST, FELLOWS, SCHOLARS AND OTHER MEMBERS OF BOARD OF TRINITY COLLEGE DUBLIN (IE) | 2023-07-06 | — | — | US | disclosed |
| US-11342558-B2 | Surface modification | NEXEON LIMITED (GB) | 2022-05-24 | — | — | US | disclosed |
| US-20220123282-A1 | Electroactive Materials for Metal-Ion Batteries | NEXEON LIMITED (GB) | 2022-04-21 | — | — | US | disclosed |
| US-20220077457-A1 | ELECTROACTIVE MATERIALS FOR METAL-ION BATTERIES | NEXEON LIMITED (GB) | 2022-03-10 | — | — | US | disclosed |
| EP-3638622-A1 | ELECTROACTIVE MATERIALS FOR METAL-ION BATTERIES | Nexeon Ltd. (GB) | 2020-04-22 | — | — | EP | disclosed |
| US-20200099043-A1 | ELECTROACTIVE MATERIALS FOR METAL-ION BATTERIES | NEXEON LIMITED (GB) | 2020-03-26 | — | — | US | disclosed |
| CN-110753674-A | Electroactive material for metal ion batteries | 奈克松有限公司 | 2020-02-04 | — | — | CN | disclosed |
| EP-3295500-B1 | SURFACE MODIFICATION | NEXEON LTD (GB) | 2019-01-02 | — | — | EP | disclosed |
| WO-2018229515-A1 | ELECTROACTIVE MATERIALS FOR METAL-ION BATTERIES | NEXEON LIMITED (GB) | 2018-12-20 | — | — | WO | disclosed |
| US-20180331364-A1 | Surface Modification | NEXEON LIMITED (GB) | 2018-11-15 | — | — | US | disclosed |
| US-20180331353-A1 | Functionalised Electrochemically Active Material and Method of Functionalisation | NEXEON LIMITED (GB) | 2018-11-15 | — | — | US | disclosed |
| EP-3295499-B1 | FUNCTIONALISED ELECTROCHEMICALLY ACTIVE MATERIAL AND METHOD OF FUNCTIONALISATION | NEXEON LTD (GB) | 2018-10-24 | — | — | EP | disclosed |
| EP-3295500-A1 | SURFACE MODIFICATION | Nexeon Limited (GB) | 2018-03-21 | — | — | EP | disclosed |
| EP-3295499-A1 | FUNCTIONALISED ELECTROCHEMICALLY ACTIVE MATERIAL AND METHOD OF FUNCTIONALISATION | Nexeon Limited (GB) | 2018-03-21 | — | — | EP | disclosed |