Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.35 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.35 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.32 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.31 |
| ▸ | LCK | P06239 | 1/20 | 0.31 |
| ▸ | FYN | P06241 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL6633487 | 0.90 | FFAR3 (0.47) | LMNAALDH1A1HCAR2KEAP1NFE2L2 | |
| Acetic Acid SCHEMBL6633787 | 0.90 | FFAR3 (0.47) | LMNAALDH1A1HCAR2KEAP1NFE2L2 | |
| Acetic Acid SCHEMBL73619 | 0.90 | FFAR3 (0.47) | LMNAALDH1A1HCAR2KEAP1NFE2L2 | |
| Acetic Acid SCHEMBL6761218 | 0.90 | FFAR3 (0.47) | LMNAALDH1A1HCAR2KEAP1NFE2L2 | |
| Bicarbonate SCHEMBL226943 | 0.89 | LMNA (0.50) | LMNAALDH1A1CA1CA2CA9 | |
| Bicarbonate SCHEMBL325796 | 0.89 | LMNA (0.50) | LMNAALDH1A1CA1CA2CA9 | |
| Bicarbonate SCHEMBL28734227 | 0.89 | LMNA (0.50) | LMNAALDH1A1CA1CA2CA9 | |
| Bicarbonate SCHEMBL21612732 | 0.89 | LMNA (0.50) | LMNAALDH1A1CA1CA2CA9 | |
| Bicarbonate SCHEMBL20954184 | 0.89 | LMNA (0.50) | LMNAALDH1A1CA1CA2CA9 | |
| Bicarbonate SCHEMBL29150348 | 0.89 | LMNA (0.50) | LMNAALDH1A1CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114824164-B | Lithium ion battery cathode, preparation method thereof and lithium ion battery | 比亚迪股份有限公司 | 2022-10-18 | — | — | CN | disclosed |
| CN-114824164-A | Lithium ion battery cathode, preparation method thereof and lithium ion battery | 比亚迪股份有限公司 | 2022-07-29 | — | — | CN | disclosed |