SCHEMBL29131365

SCHEMBL29131365

CCOP(=O)(C[S@@+]([O-])c1cccc(F)c1)OCC

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 1/20 0.37
CA1 P00915 1/20 0.37
CA2 P00918 1/20 0.37
CA9 Q16790 1/20 0.37
LMNA P02545 4/20 0.33
MMP9 P14780 2/20 0.32
MMP1 P03956 1/20 0.32
MMP3 P08254 1/20 0.32
ADAM17 P78536 1/20 0.32
ADAM9 Q13443 1/20 0.32
ALDH1A1 P00352 1/20 0.32
MAPT P10636 1/20 0.32
MAPK1 P28482 1/20 0.32
MEN1 O00255 1/20 0.32
GAA P10253 1/20 0.32
KMT2A Q03164 1/20 0.32
POLB P06746 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
TSHR P16473 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29131311 0.82 ALDH1A1 (0.38) CA12CA1CA2CA9LMNA
SCHEMBL30811022 0.82 ALDH1A1 (0.38) CA12CA1CA2CA9LMNA
SCHEMBL1330697 0.82 NPSR1 (0.43) CA12CA1CA2CA9LMNA
SCHEMBL17050984 0.82 NPSR1 (0.43) CA12CA1CA2CA9LMNA
SCHEMBL777297 0.74 ACHE (0.40)
SCHEMBL19822546 0.74 TSHR (0.36) CA12CA1CA2CA9ALDH1A1
SCHEMBL29131324 0.73 KMT2A (0.36) CA12CA1CA2CA9LMNA
SCHEMBL19828141 0.72 LMNA (0.37) LMNAMEN1GAAKMT2ATSHR
SCHEMBL19828208 0.71 LTA4H (0.44) CA12CA1CA2CA9LMNA
SCHEMBL29938481 0.71 IDO1 (0.43) LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117303992-A Preparation method of polyfunctional group substituted chiral sulfoxide compound 厦门大学 2023-12-29 CN claimed