Pyridine

Pyridine

SCHEMBL29132370

COB(O)Cc1ccccc1.c1ccncc1

nearest known ligand 0.41

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP11B1 P15538 1/20 0.36
CYP11B2 P19099 1/20 0.36
LIPE Q05469 1/20 0.36
CA1 P00915 1/20 0.35
CA2 P00918 1/20 0.35
SLC6A2 P23975 1/20 0.35
SLC6A4 P31645 1/20 0.35
SLC6A3 Q01959 1/20 0.35
TDP1 Q9NUW8 2/20 0.35
POLB P06746 1/20 0.35
LMNA P02545 1/20 0.35
KMT2A Q03164 1/20 0.35
NAPRT Q6XQN6 2/20 0.34
CYP1A2 P05177 4/20 0.34
CYP3A4 P08684 4/20 0.34
CYP2C9 P11712 4/20 0.34
CYP2C19 P33261 4/20 0.34
CYP2D6 P10635 3/20 0.34
HIF1A Q16665 2/20 0.34
KCNA5 P22460 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3900187 0.90 CA1 (0.41) LIPECA1CA2TDP1ALDH1A1
Pyridine SCHEMBL1581039 0.78 CA1 (0.46) CA1CA2SLC6A2SLC6A4SLC6A3
SCHEMBL23535576 0.75 LIPE (0.39) LIPECA1CA2TDP1LMNA
Pyridine SCHEMBL29132336 0.73 ENPP2 (0.39) CA1CA2TDP1KMT2ANAPRT
Pyridine SCHEMBL29154353 0.71 TSHR (0.47) TDP1NAPRTTSHR
SCHEMBL3796769 0.70 CTRB1 (0.47) CA1CA2KMT2ACYP2C9CYP2C19
SCHEMBL1356582 0.70 CA1 (0.41) LIPECA1CA2TDP1LMNA
Pyridine SCHEMBL638445 0.69 CYP19A1 (0.56) LMNAKMT2ACYP19A1ALDH1A1GAA
SCHEMBL3901460 0.69 TP53 (0.42) TDP1CYP3A4ALDH1A1MAPTLTA4H
Ethylbenzene SCHEMBL8652916 0.69 TP53 (0.70) SLC6A2SLC6A4SLC6A3TDP1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116973436-A Mass spectrum imaging detection method for compound containing ortho-diphenol hydroxyl functional group in tissue 中国科学院大连化学物理研究所 2023-10-31 CN claimed