Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR5 | P51681 | 3/20 | 0.33 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.32 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29626302 | 1.00 | CCR5 (0.33) | CCR5TMEM97TRPM8L3MBTL1HTR2A | |
| SCHEMBL25338987 | 0.93 | CCR5 (0.35) | CCR5TMEM97TRPM8HTR2A | |
| SCHEMBL29626474 | 0.85 | CA1 (0.41) | L3MBTL1 | |
| SCHEMBL29024337 | 0.85 | CA1 (0.41) | L3MBTL1 | |
| SCHEMBL29626395 | 0.85 | CA1 (0.38) | L3MBTL1 | |
| SCHEMBL29626309 | 0.84 | ACACB (0.33) | — | |
| SCHEMBL25339147 | 0.81 | CA1 (0.39) | L3MBTL1 | |
| SCHEMBL25194894 | 0.80 | L3MBTL1 (0.31) | L3MBTL1 | |
| SCHEMBL25339103 | 0.80 | ACACB (0.33) | — | |
| SCHEMBL29024310 | 0.80 | GABRP (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116829555-A | Protein tyrosine phosphatase inhibitors and methods of use thereof | 卡里科生命科学有限责任公司 | 2023-09-29 | — | — | CN | disclosed |