Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR5 | P51681 | 8/20 | 0.38 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.38 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | MC4R | P32245 | 1/20 | 0.34 |
| ▸ | CCRL2 | O00421 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25338313 | 0.86 | TRPM8 (0.40) | CCR5TRPM8TMEM97HTR2AMC4R | |
| SCHEMBL29626448 | 0.86 | TRPM8 (0.38) | CCR5TRPM8TMEM97HTR2AMC4R | |
| SCHEMBL29132471 | 0.79 | RORC (0.35) | CCR5HTR2ACA1CA2ACHE | |
| SCHEMBL29626362 | 0.76 | HTR2A (0.35) | CCR5HTR2ACCRL2CA1CA2 | |
| SCHEMBL29626276 | 0.75 | HTR2A (0.38) | CCR5TRPM8HTR2AMC4RCA1 | |
| SCHEMBL29132505 | 0.75 | HTR2A (0.38) | CCR5HTR2AMC4RCA1CA2 | |
| SCHEMBL29132480 | 0.75 | HTR2A (0.38) | CCR5TRPM8HTR2AMC4RCA1 | |
| SCHEMBL29626302 | 0.74 | CCR5 (0.33) | CCR5TRPM8TMEM97HTR2A | |
| SCHEMBL29132492 | 0.74 | CCR5 (0.33) | CCR5TRPM8TMEM97HTR2A | |
| SCHEMBL25338987 | 0.73 | CCR5 (0.35) | CCR5TRPM8TMEM97HTR2AMC4R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116829555-A | Protein tyrosine phosphatase inhibitors and methods of use thereof | 卡里科生命科学有限责任公司 | 2023-09-29 | — | — | CN | disclosed |