Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 7/20 | 0.98 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.98 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.98 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | ATM | Q13315 | 1/20 | 0.59 |
| ▸ | CA2 | P00918 | 3/20 | 0.57 |
| ▸ | CA1 | P00915 | 2/20 | 0.57 |
| ▸ | CA7 | P43166 | 2/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | CA12 | O43570 | 1/20 | 0.57 |
| ▸ | CA4 | P22748 | 1/20 | 0.57 |
| ▸ | CA6 | P23280 | 1/20 | 0.57 |
| ▸ | CA5A | P35218 | 1/20 | 0.57 |
| ▸ | CA9 | Q16790 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30561876 | 1.00 | LMNA (0.98) | LMNACYP2C9ADRA2BTDP1ALDH1A1 | |
| Cyclopenthiazide SCHEMBL49142 | 0.99 | LMNA (1.00) | LMNACYP2C9ADRA2BTDP1ALDH1A1 | |
| Cyclopenthiazide SCHEMBL30561852 | 0.99 | LMNA (1.00) | LMNACYP2C9ADRA2BTDP1ALDH1A1 | |
| Cyclopenthiazide SCHEMBL9505656 | 0.97 | LMNA (0.96) | LMNACYP2C9ADRA2BTDP1ALDH1A1 | |
| Cyclopenthiazide SCHEMBL13723122 | 0.91 | LMNA (0.85) | LMNACYP2C9ADRA2BTDP1ALDH1A1 | |
| Cyclopenthiazide SCHEMBL28832656 | 0.86 | LMNA (0.76) | LMNACYP2C9ADRA2BTDP1ALDH1A1 | |
| Cyclopenthiazide SCHEMBL28142871 | 0.86 | LMNA (0.76) | LMNACYP2C9ADRA2BTDP1ALDH1A1 | |
| Cyclothiazide SCHEMBL28279779 | 0.85 | LMNA (0.78) | LMNACYP2C9ADRA2BTDP1ALDH1A1 | |
| SCHEMBL17471640 | 0.83 | LMNA (0.72) | LMNACYP2C9ADRA2BTDP1ALDH1A1 | |
| SCHEMBL13685945 | 0.82 | TDP1 (0.79) | LMNACYP2C9ADRA2BTDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116836130-B | Synthesis method of 3, 4-dihydrobenzothiadiazine compound | 嘉实（湖南）医药科技有限公司 | 2023-11-21 | — | — | CN | disclosed |
| CN-116836130-A | Synthesis method of 3, 4-dihydrobenzothiadiazine compound | 嘉实（湖南）医药科技有限公司 | 2023-10-03 | — | — | CN | disclosed |