Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 7/20 | 1.00 |
| ▸ | CYP2C9 | P11712 | 3/20 | 1.00 |
| ▸ | ADRA2B | P18089 | 1/20 | 1.00 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.63 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.63 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.63 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.60 |
| ▸ | HPGD | P15428 | 1/20 | 0.60 |
| ▸ | ATM | Q13315 | 1/20 | 0.60 |
| ▸ | CA2 | P00918 | 3/20 | 0.58 |
| ▸ | CA1 | P00915 | 2/20 | 0.58 |
| ▸ | CA7 | P43166 | 2/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | CA12 | O43570 | 1/20 | 0.58 |
| ▸ | CA4 | P22748 | 1/20 | 0.58 |
| ▸ | CA6 | P23280 | 1/20 | 0.58 |
| ▸ | CA5A | P35218 | 1/20 | 0.58 |
| ▸ | CA9 | Q16790 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cyclopenthiazide SCHEMBL30561852 | 1.00 | LMNA (1.00) | LMNACYP2C9ADRA2BTDP1ALDH1A1 | |
| SCHEMBL29132641 | 0.99 | LMNA (0.98) | LMNACYP2C9ADRA2BTDP1ALDH1A1 | |
| SCHEMBL30561876 | 0.99 | LMNA (0.98) | LMNACYP2C9ADRA2BTDP1ALDH1A1 | |
| Cyclopenthiazide SCHEMBL9505656 | 0.98 | LMNA (0.96) | LMNACYP2C9ADRA2BTDP1ALDH1A1 | |
| Cyclopenthiazide SCHEMBL13723122 | 0.92 | LMNA (0.85) | LMNACYP2C9ADRA2BTDP1ALDH1A1 | |
| Cyclopenthiazide SCHEMBL28832656 | 0.87 | LMNA (0.76) | LMNACYP2C9ADRA2BTDP1ALDH1A1 | |
| Cyclopenthiazide SCHEMBL28142871 | 0.87 | LMNA (0.76) | LMNACYP2C9ADRA2BTDP1ALDH1A1 | |
| Cyclothiazide SCHEMBL28279779 | 0.86 | LMNA (0.78) | LMNACYP2C9ADRA2BTDP1ALDH1A1 | |
| SCHEMBL17471640 | 0.84 | LMNA (0.72) | LMNACYP2C9ADRA2BTDP1ALDH1A1 | |
| SCHEMBL13685945 | 0.83 | TDP1 (0.79) | LMNACYP2C9ADRA2BTDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 5045 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4722714-A1 | SIMULTANEOUS ANALYSIS OF FOOD-BORNE DOPING SUBSTANCES USING LIQUID CHROMATOGRAPHY-MASS SPECTROMETRY (VFD: VACCINE FOR FOODBORNE DOPING) | Korea Institute of Science and Technology (KR) | 2026-04-08 | — | — | EP | claimed |
| US-12529704-B2 | Methods for objective assessment of stress, early detection of risk for stress disorders, matching individuals with treatments, monitoring response to treatment, and new methods of use for drugs | INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) | 2026-01-20 | — | — | US | claimed |
| US-20250057876-A1 | METHODS FOR TREATING AND/OR PREVENTING LYMPHANGIOGENESIS-ASSOCIATED DISEASES BY USING GOLD NANOCLUSTERS | GOLDRED NANOBIOTECH CO., LTD. (TW) | 2025-02-20 | — | — | US | claimed |
| US-12203941-B2 | Methods and compositions for diagnosis and prognosis of renal injury and renal failure | ASTUTE MEDICAL, INC. (US) | 2025-01-21 | — | — | US | claimed |
| CN-117825540-A | Method for rapidly screening and detecting illegal drugs added to food for relieving alcoholism | 广电计量检测集团股份有限公司 | 2024-04-05 | — | — | CN | claimed |
| US-20240002935-A1 | GENETIC METHOD FOR DIAGNOSIS AND TREATMENT OF PRE AND POST CORONAVIRUS INFECTIONS | GENETICURE INC. | 2024-01-04 | — | — | US | claimed |
| WO-2023183932-A2 | MONOBODIES BINDING TO INTERCELLULAR ADHESION MOLECULE 2 (ICAM-2) | NEW YORK UNIVERSITY (US) | 2023-09-28 | — | — | WO | claimed |
| CN-116603066-A | Composition for treating hypertension | 乔治全球健康研究院 | 2023-08-18 | — | — | CN | claimed |
| US-20230134747-A1 | COMPOSITIONS FOR THE TREATMENT OF AUTISM SPECTRUM DISORDER | STALICLA SA (CH) | 2023-05-04 | — | — | US | claimed |
| CN-115811974-A | Compositions for treating autism spectrum disorders | 斯塔利克拉股份有限公司 | 2023-03-17 | — | — | CN | claimed |
| US-4867985-A | CONTROLLED RELEASE OF NON-STEROID ANTIINFLAMMATORY AGENTS | EUROCELTIQUE S.A. (LU) | 1989-09-19 | — | — | US | claimed |
| US-4769236-A | Medicaments with a high degree of solubility and method for their production | ELAN CORPORATION, PLC (IE) | 1988-09-06 | — | — | US | claimed |
| US-4557934-A | ALONG WITH A DIOL PYRROLIDONE OR AN AZACYCLOPENTAN-2-ONE | THE PROCTER & GAMBLE COMPANY (US) | 1985-12-10 | — | — | US | claimed |
| EP-0154009-A1 | Use of a thiazide diuretic for the manufacture of a non-diuretic antihypertensive medicament | Euro-Celtique S.A. (LU) | 1985-09-11 | — | — | EP | claimed |
| EP-0011818-B1 | MEDICAMENTS AND PHARMACEUTICAL COMPOSITIONS BASED ON ALDOSTERONE ANTAGONISTS AND DIURETICS AND PROCESS FOR THEIR MANUFACTURE | CIBA-GEIGY AG (CH) | 1983-01-19 | — | — | EP | claimed |
| US-4265893-A | 2,4-DIAMINO-5-(4-AMINO-3,5-DIALKOXY BENZYL) PYRIMIDINE AS POTASSIUM RETAINING COMPOUND | HOFFMANN-LA ROCHE INC. (US) | 1981-05-05 | — | — | US | claimed |
| US-4261985-A | REDUCED EXCRETION OF POTASSIUM IONS BY INCLUSION OF ALDOSTERONE ANTAGONIST | CIBA-GEIGY CORPORATION (US) | 1981-04-14 | — | — | US | claimed |
| US-4238485-A | 1,2,5-THIADIAZOLE DERIVATIVE, THIAZIDE DIURETIC, HYPOTENSIVE AGENTS | MERCK & CO., INC. (US) | 1980-12-09 | — | — | US | claimed |
| US-4178374-A | SUBSTITUTED 1,2,5-THIADIAZOLE B-ADRENERGIC BLOCKING AGENT, PYRAZINE AND/OR THIAZIDE DIURETIC, TREATMENT OF HYPERTENSION | MERCK & CO., INC. (US) | 1979-12-11 | — | — | US | claimed |
| US-4075335-A | HYPOTENSIVE AGENTS | CIBA-GEIGY CORPORATION (US) | 1978-02-21 | — | — | US | claimed |