Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | CTSL | P07711 | 1/20 | 0.43 |
| ▸ | CTSB | P07858 | 1/20 | 0.43 |
| ▸ | CTSK | P43235 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.41 |
| ▸ | MTOR | P42345 | 1/20 | 0.41 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.40 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.40 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.40 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.40 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.40 |
| ▸ | PSENEN | Q9NZ42 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | AGXT | P21549 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.39 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.39 |
| ▸ | DPP4 | P27487 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL582674 | 0.78 | CTSL (0.50) | TSHRCTSLCTSBCTSKIDO1 | |
| SCHEMBL29132687 | 0.78 | CTSL (0.50) | TSHRCTSLCTSBCTSKIDO1 | |
| SCHEMBL22341050 | 0.74 | CYP2C19 (0.41) | TSHRCTSLCTSBCTSKPSEN1 | |
| SCHEMBL21000277 | 0.73 | CTSL (0.43) | CTSLCTSBCTSKPDPK1MTOR | |
| SCHEMBL6053680 | 0.72 | TSHR (0.52) | TSHRCTSLCTSBCTSKIDO1 | |
| SCHEMBL5663072 | 0.72 | TSHR (0.52) | TSHRCTSLCTSBCTSKIDO1 | |
| SCHEMBL23258242 | 0.72 | CARM1 (0.46) | CTSLCTSBCTSKPSEN1PSEN2 | |
| SCHEMBL6469380 | 0.71 | OPRM1 (0.59) | TSHRCTSLCTSBCTSKIDO1 | |
| SCHEMBL1929688 | 0.71 | CRBN (0.44) | CTSLCTSBCTSKPSEN1PSEN2 | |
| SCHEMBL1930872 | 0.71 | PSEN1 (0.41) | TSHRCTSLCTSBCTSKPDPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220170904-A1 | SYSTEMS AND METHODS FOR MONITORING BIOLOGICAL TISSUE DEGRADATION | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) | 2022-06-02 | — | — | US | disclosed |