SCHEMBL2913292

SCHEMBL2913292

Cc1cc(C(F)(C(F)(F)F)C(F)(F)F)ccc1NC(=O)c1cccc(OC(F)(F)F)c1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 4/20 0.51
HTT P42858 2/20 0.51
LMNA P02545 1/20 0.51
MAPT P10636 1/20 0.51
HSD17B10 Q99714 1/20 0.51
DHODH Q02127 1/20 0.51
GAA P10253 2/20 0.50
CYP1A2 P05177 1/20 0.49
CYP3A4 P08684 1/20 0.49
CYP2D6 P10635 1/20 0.49
CYP2C19 P33261 1/20 0.49
NPSR1 Q6W5P4 1/20 0.48
NPC1 O15118 2/20 0.48
RAB9A P51151 2/20 0.48
POLB P06746 1/20 0.48
IGF2BP2 Q9Y6M1 1/20 0.47
BRAF P15056 4/20 0.47
RAF1 P04049 1/20 0.47
LCK P06239 1/20 0.47
RET P07949 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6676510 0.83 IGF2BP2 (0.62) MAPTDHODHGAACYP1A2CYP2C19
SCHEMBL5429717 0.82 POLB (0.54) SMN1; SMN2MAPTGAACYP1A2CYP2C19
SCHEMBL22212751 0.76 GAA (0.52) MAPTGAACYP1A2CYP2C19NPC1
SCHEMBL13329272 0.76 HSP90AA1 (0.58) SMN1; SMN2LMNAMAPTGAANPC1
SCHEMBL2916215 0.76 DHODH (0.43) MAPTDHODHNPSR1NPC1RAB9A
SCHEMBL20271750 0.75 RAB9A (0.54) SMN1; SMN2LMNAMAPTGAANPC1
SCHEMBL27926141 0.75 MAPT (0.55) SMN1; SMN2HTTLMNAMAPTGAA
SCHEMBL4181080 0.75 RXFP1 (0.55) SMN1; SMN2GAA
SCHEMBL14200567 0.74 MEN1 (0.67) SMN1; SMN2HTTMAPTGAACYP1A2
SCHEMBL18525797 0.74 TAS1R3 (0.59) NPC1RAB9ARAF1TAS1R3TAS1R1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1006107-B1 Phthalamide derivatives, or salt thereof agrohorticultural insecticide, and method for using the same NIHON NOHYAKU CO LTD (JP) 2010-09-01 EP disclosed
US-6603044-B1 The present invention provides a phthalamide derivative of the formula (I): agrohorticultural insecticide containing said compound as active ingredient and exhibiting an excellent insecticidal effect. NIHON NOHYAKU CO., LTD. (JP) 2003-08-05 US disclosed
EP-1006107-A2 Phthalamide derivatives, or salt thereof agrohorticultural insecticide, and method for using the same NIHON NOHYAKU CO., LTD. (JP) 2000-06-07 EP disclosed