Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.37 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 5/20 | 0.34 |
| ▸ | MAPT | P10636 | 4/20 | 0.34 |
| ▸ | LMNA | P02545 | 4/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.31 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.31 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.31 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29132973 | 0.75 | ALDH1A1 (0.38) | TLR8TLR7MAPTLMNAALDH1A1 | |
| SCHEMBL29133055 | 0.73 | ALDH1A1 (0.52) | TLR8TLR7MAPTALDH1A1TLR9 | |
| SCHEMBL29133064 | 0.67 | NOTUM (0.43) | TSHRMAPTLMNAKMT2AHTT | |
| SCHEMBL29133160 | 0.67 | SMN1; SMN2 (0.41) | TLR8TLR7MAPTLMNAKMT2A | |
| SCHEMBL29133017 | 0.66 | DGAT1 (0.50) | TLR8TLR7MAPTLMNAKMT2A | |
| SCHEMBL12098306 | 0.65 | KMT2A (0.61) | TSHRMAPTLMNAKMT2ANPSR1 | |
| SCHEMBL12098303 | 0.65 | KMT2A (0.61) | TSHRMAPTLMNAKMT2ANPSR1 | |
| SCHEMBL30622248 | 0.65 | KDM4E (0.49) | MAPTLMNAKMT2ANPSR1MEN1 | |
| SCHEMBL15099854 | 0.64 | ALDH1A1 (0.50) | TLR8TLR7TSHRMAPTLMNA | |
| SCHEMBL22602035 | 0.63 | ALDH1A1 (0.54) | TSHRMAPTLMNAKMT2ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117088884-A | Imidazopyridazine derivatives as GABAA receptor modulators, pharmaceutical compositions and uses | 上海赛默罗德生物科技有限公司 | 2023-11-21 | — | — | CN | disclosed |