Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | CDK1 | P06493 | 1/20 | 0.47 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | CFTR | P13569 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30643025 | 1.00 | MEN1 (0.50) | MEN1KMT2ACDK1CCNB1LMNA | |
| SCHEMBL19786040 | 0.86 | KDM4E (0.46) | MEN1KMT2ALMNAKDM4EALDH1A1 | |
| SCHEMBL18658587 | 0.84 | ALDH1A1 (0.42) | MEN1KMT2ALMNAKDM4EALDH1A1 | |
| SCHEMBL17294318 | 0.84 | MEN1 (0.43) | MEN1KMT2ACDK1CCNB1LMNA | |
| SCHEMBL17298254 | 0.84 | MEN1 (0.43) | MEN1KMT2ACDK1CCNB1LMNA | |
| Hydrochloric Acid SCHEMBL21354321 | 0.83 | ALDH1A1 (0.43) | MEN1KMT2ACDK1CCNB1LMNA | |
| SCHEMBL17295858 | 0.81 | MEN1 (0.40) | MEN1KMT2ACDK1CCNB1LMNA | |
| SCHEMBL17304365 | 0.81 | MEN1 (0.40) | MEN1KMT2ACDK1CCNB1LMNA | |
| SCHEMBL20614115 | 0.77 | MEN1 (0.43) | MEN1KMT2ACDK1CCNB1KDM4E | |
| SCHEMBL22383760 | 0.76 | LMNA (0.45) | MEN1KMT2ACDK1CCNB1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117285485-A | Bis-sulfonamide derivative and preparation method and application thereof | 复旦大学 | 2023-12-26 | — | — | CN | disclosed |