Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | CACNB4 | O00305 | 1/20 | 0.40 |
| ▸ | CACNA1A | O00555 | 1/20 | 0.40 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.40 |
| ▸ | CACNG3 | O60359 | 1/20 | 0.40 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.40 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.40 |
| ▸ | CACNB3 | P54284 | 1/20 | 0.40 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.40 |
| ▸ | CACNG7 | P62955 | 1/20 | 0.40 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30643025 | 0.86 | MEN1 (0.50) | KDM4EGAAALDH1A1TP53LMNA | |
| SCHEMBL29133046 | 0.86 | MEN1 (0.50) | KDM4EGAAALDH1A1TP53LMNA | |
| SCHEMBL18658587 | 0.86 | ALDH1A1 (0.42) | KDM4EGAAALDH1A1TP53LMNA | |
| SCHEMBL19785974 | 0.75 | LMNA (0.47) | LMNAMEN1KMT2A | |
| SCHEMBL9621558 | 0.74 | ACHE (0.65) | KDM4EALDH1A1LMNAMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL2925348 | 0.72 | ACHE (0.63) | KDM4EALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL16463510 | 0.72 | ALDH1A1 (0.40) | KDM4EGAAALDH1A1L3MBTL1MEN1 | |
| SCHEMBL21354275 | 0.72 | THRB (0.40) | KDM4EALDH1A1ACHE | |
| Hydrochloric Acid SCHEMBL7428600 | 0.71 | ALDH1A1 (0.49) | KDM4EALDH1A1LMNAL3MBTL1MEN1 | |
| SCHEMBL18658604 | 0.71 | ALDH1A1 (0.46) | KDM4EGAAALDH1A1LMNACYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018011201-A1 | HETEROAROMATIC MODULATORS OF THE RETINOID-RELATED ORPHAN RECEPTOR GAMMA | LEO PHARMA A/S (DK) | 2018-01-18 | — | — | WO | disclosed |